Oral plasma-cell mucositis exacerbated by qat chewing – A case series

Abstract

Plasma-cell mucositis (PCM) is a rare idiopathic condition that affects the mucus membrane at one or more of the body orifices. We hereby present eight cases of oral PCM associated with qat chewing. The patients (all males, 20–33 years old) presented with chronic painful inflammatory mucosal lesions involving different sites of the oral cavity, particularly the gingiva. An erythematous and swollen gingiva with velvety surface was a typical feature. Areas of epithelial sloughing and/or erosions were also noticed. In seven patients, the lesion also affected the tongue, palate, lip and/or buccal mucosa. Hoarseness was observed in some of the patients suggesting laryngeal involvement. The symptoms correlated with patterns of qat chewing. Histological examination revealed dense infiltration of lamina propria by benign plasma cells. Lymphocytosis and/or elevated IgG titer were the main laboratory findings. This provides further evidence that PCM can at least be exacerbated by the habit of qat chewing.