G. Wenska, Katarzyna Taras-Goślińska, Katarzyna Lamparska-Kupsik, B. Skalski, M. Gdaniec, Z. Gdaniec
{"title":"Photochemical transformations of 5-halogeno-4-thiouridines","authors":"G. Wenska, Katarzyna Taras-Goślińska, Katarzyna Lamparska-Kupsik, B. Skalski, M. Gdaniec, Z. Gdaniec","doi":"10.1039/B108380E","DOIUrl":null,"url":null,"abstract":"A series of 2′,3′,5′-tri-O-acetyl-5-halogeno-4-thiouridines, where halogen = Br, Cl, F, are synthesized and their photochemical transformations upon irradiation with near-UV light (λ > 300 nm) in aqueous acetonitrile solutions investigated. The main photochemical pathways in each case involve intermolecular additions leading to three main photoproducts with different relative distributions. The photoproducts are isolated and their structures determined based on MS, 1H and 13C NMR and UV spectral data.","PeriodicalId":17267,"journal":{"name":"Journal of The Chemical Society-perkin Transactions 1","volume":"65 1","pages":"53-57"},"PeriodicalIF":0.0000,"publicationDate":"2002-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of The Chemical Society-perkin Transactions 1","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1039/B108380E","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
A series of 2′,3′,5′-tri-O-acetyl-5-halogeno-4-thiouridines, where halogen = Br, Cl, F, are synthesized and their photochemical transformations upon irradiation with near-UV light (λ > 300 nm) in aqueous acetonitrile solutions investigated. The main photochemical pathways in each case involve intermolecular additions leading to three main photoproducts with different relative distributions. The photoproducts are isolated and their structures determined based on MS, 1H and 13C NMR and UV spectral data.