COVID-19 and heart failure

N. Tsabedze, S. Kraus, J. Hitzeroth, M. Ntsekhe, Martin Mpe, M. Makotoko
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Abstract

Acute and chronic heart failure patients have a 2- to 3-fold increased risk of complicating with severe COVID-19, and these patients tend to have multiple comorbidities which are the primary aetiologies for the heart failure clinical syndrome. Furthermore, the incidence and prevalence of heart failure increases with advanced age, and advanced age is an independent risk factor for poor prognosis and mortality. The SARSCoV-2 infection also has multiple mechanisms that cause acute heart failure and precipitate acutely decompensated chronic heart failure. Additionally, the optimal management of these patients has been marred with the controversy around the use of the renin-angiotensin-aldosterone system blockers. This review provides an update on how heart failure patients should be managed during COVID-19 and summarises the existing evidence, focusing on heart failure.
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COVID-19和心力衰竭
急性和慢性心力衰竭患者合并严重COVID-19的风险增加2- 3倍,这些患者往往有多种合并症,这些合并症是心力衰竭临床综合征的主要病因。此外,心力衰竭的发病率和患病率随着年龄的增长而增加,高龄是预后不良和死亡的独立危险因素。SARSCoV-2感染也有多种机制,可导致急性心力衰竭和急性失代偿性慢性心力衰竭。此外,这些患者的最佳管理已被围绕使用肾素-血管紧张素-醛固酮系统阻滞剂的争议所损害。本综述提供了COVID-19期间心力衰竭患者应如何治疗的最新信息,并总结了现有证据,重点是心力衰竭。
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12
审稿时长
7 weeks
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