Repeatability and Reproducibility of Axial Length Obtained by the IOLMaster 500 in 2 – 6 Year-Old Children

Guanshun Yu, Q. Zheng, Yili Jin, Hengli Lian, Miaojun Yan, Ruru Chen, Qin-Mei Wang
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Abstract

Objective: To assess the repeatability and reproducibility of axial length obtained by the optical biometer IOLMaster 500 in children aged 2-6 years. Methods: One hundred and two right eyes from 102 children were included in this cross-sectional study from Eye Hospital, Wenzhou Medical University from December 2016 to March 2017. Each eye was measured by two experienced operators using the IOLMaster 500 with 3 consecutive measurements. To evaluate intraoperator repeatability using repeated measurement ANOVA, Bland-Altman plots, and use paired samples t test and so on to analyze data. Results: The axial length obtained by the IOLMaster 500 showed high repeatability (95%LoA within -0.04 to 0.04 mm, and ICC was 1.000). The reproducibility of axial length was also high (95%LoA within -0.04 to 0.03 mm, Sw<0.01mm, 2.77 Sw<0.03 mm, CoV<0.05%). The width of the 95%LoA was reduced by 42.86% using averaged results rather than the result of a single measurement. Conclusions: Axial lengths obtained by the IOLMaster 500 in children aged 2-6 years shows high repeatability and reproducibility. In addition, the mean value of 3 consecutive measurements is better than that of a single measurement. Key words: IOLMaster 500; axial length; A scan; repeatability; reproducibility; children
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iolmaster500测定2 - 6岁儿童眼轴长度的重复性和再现性
目的:评价光学生物计IOLMaster 500测定眼球轴长在2 ~ 6岁儿童中的重复性和再现性。方法:选取2016年12月至2017年3月温州医科大学眼科医院102例患儿的102只右眼进行横断面研究。每只眼睛由两名经验丰富的操作员使用IOLMaster 500进行3次连续测量。采用重复测量方差分析、Bland-Altman图、配对样本t检验等方法评价操作者内部重复性。结果:IOLMaster 500测定的轴向长度具有较高的重复性(95%LoA在-0.04 ~ 0.04 mm范围内,ICC为1.000)。轴向长度的重现性也较高(95%LoA在-0.04 ~ 0.03 mm范围内,Sw<0.01mm, 2.77 Sw<0.03 mm, CoV<0.05%)。使用平均结果而不是单次测量结果,95%LoA的宽度减小了42.86%。结论:IOLMaster 500测定的2-6岁儿童眼轴长度具有较高的重复性和再现性。此外,连续3次测量的平均值优于单次测量的平均值。关键词:iolmaster500;轴向长度;一个扫描;可重复性;再现性;孩子们
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