Inhaled antiseptics and inhaled antiviral non-prescription drugs in the prevention of ARVI, in particular COVID-19: an epidemiological study

Y. Feshchenko, M. Gumeniuk, М. Lynnyk, O. Dziublyk, M. Kuzhko, О. Tereshkovych, O. Khmel, I. Panashchuk, M.V. Yashchenko, Оleksiy S. Denysov, Т.А. Sprynsian
{"title":"Inhaled antiseptics and inhaled antiviral non-prescription drugs in the prevention of ARVI, in particular COVID-19: an epidemiological study","authors":"Y. Feshchenko, M. Gumeniuk, М. Lynnyk, O. Dziublyk, M. Kuzhko, О. Tereshkovych, O. Khmel, I. Panashchuk, M.V. Yashchenko, Оleksiy S. Denysov, Т.А. Sprynsian","doi":"10.32902/2663-0338-2021-4-5-15","DOIUrl":null,"url":null,"abstract":"BACKGROUND. The article presents the results of a continuous, cross-sectional, non-interventional, multicenter retrospective epidemiological study, which included cases of 3443 participants. Questionnaires and rapid test for antibodies to SARS-CoV-2 were used to collect data. \nOBJECTIVE. To determine the relationship between the systematic use of additional drugs for the prevention of COVID-19, including inhaled antiseptics and inhaled antiviral drugs, separately and in combination with other drugs, and the risk of developing of coronavirus disease (COVID-19). \nRESULTS AND DISCUSSION. 396 participants (11.8 %) took inhaled antiseptics in any period since March 2020, and 410 participants (12.2 %) took inhaled antivirals. A statistically significant protective relationship between episode of COVID-19 when taking inhaled antiseptics and inhaled antiviral drugs (risk ratio 0.901; 95 % confidence interval 0.856-0.948) was determined. \nCONCLUSIONS. The use of inhaled antiseptics and inhaled antiviral drugs as additional methods of prevention of COVID-19 has shown a statistically significant effect not only on reducing the risk of COVID-19, but different combinations of inhaled antiseptics or inhaled antiviral drugs with other drug groups as additional methods of preventing COVID-19 had a statistically significant protective relationship with the episode of the disease, with the severity of COVID-19 and with the need for hospitalization.","PeriodicalId":13681,"journal":{"name":"Infusion & Chemotherapy","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infusion & Chemotherapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32902/2663-0338-2021-4-5-15","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

BACKGROUND. The article presents the results of a continuous, cross-sectional, non-interventional, multicenter retrospective epidemiological study, which included cases of 3443 participants. Questionnaires and rapid test for antibodies to SARS-CoV-2 were used to collect data. OBJECTIVE. To determine the relationship between the systematic use of additional drugs for the prevention of COVID-19, including inhaled antiseptics and inhaled antiviral drugs, separately and in combination with other drugs, and the risk of developing of coronavirus disease (COVID-19). RESULTS AND DISCUSSION. 396 participants (11.8 %) took inhaled antiseptics in any period since March 2020, and 410 participants (12.2 %) took inhaled antivirals. A statistically significant protective relationship between episode of COVID-19 when taking inhaled antiseptics and inhaled antiviral drugs (risk ratio 0.901; 95 % confidence interval 0.856-0.948) was determined. CONCLUSIONS. The use of inhaled antiseptics and inhaled antiviral drugs as additional methods of prevention of COVID-19 has shown a statistically significant effect not only on reducing the risk of COVID-19, but different combinations of inhaled antiseptics or inhaled antiviral drugs with other drug groups as additional methods of preventing COVID-19 had a statistically significant protective relationship with the episode of the disease, with the severity of COVID-19 and with the need for hospitalization.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
吸入消毒剂和吸入抗病毒非处方药预防ARVI,特别是COVID-19:一项流行病学研究
背景。本文介绍了一项连续、横断面、非介入、多中心回顾性流行病学研究的结果,其中包括3443名参与者的病例。采用问卷调查和SARS-CoV-2抗体快速检测方法收集数据。目标。确定系统使用额外的预防COVID-19药物,包括吸入性防腐剂和吸入性抗病毒药物,单独或与其他药物合用,与发生冠状病毒病(COVID-19)的风险之间的关系。结果和讨论。自2020年3月以来的任何时期,396名参与者(11.8%)吸入了防腐剂,410名参与者(12.2%)吸入了抗病毒药物。吸入消毒剂和吸入抗病毒药物时发生COVID-19的保护关系有统计学意义(风险比0.901;95%置信区间0.856 ~ 0.948)。结论。使用吸入性防腐剂和吸入性抗病毒药物作为新冠肺炎的附加预防方法,不仅在降低新冠肺炎风险方面具有统计学意义,而且不同组合使用吸入性防腐剂或吸入性抗病毒药物作为附加预防方法与疾病发作、新冠肺炎严重程度和住院需要具有统计学意义的保护关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Evaluation of the effectiveness of immunomodulator BI-V in the complex therapy of children and adolescents with multiple drug-resistant pulmonary tuberculosis Features of the course of pulmonary tuberculosis against the background of coronavirus infection according to computed tomography of the chest organs Risks of recurrence in people with pulmonary tuberculosis New and little-known possibilities of edaravone in the treatment of cerebral stroke and extracranial pathology Severe community-acquired pneumonia: principles of diagnostics and intensive therapy
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1