One Stage Procedure versus Two Stages Procedure in Management of Obstructed Non-Perforated Cancer Colon

Magdy Basheer, Mahmoud NeamatAllah, A. Abbas, M. Shetiwy
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Abstract

Background: The surgical management of large bowel emergency patients remains controversial. However, there has been an increasing trend toward primary reconstructive surgery. Objective: To evaluate one-stage procedure versus two-stage procedure in cases presented with obstructed nonperforated cancer colon in terms of operative time, hospital stay, postoperative complications, peri-operative mortality, and quality of life. Patients and methods: A prospective randomized study was conducted at Emergency Mansoura University Hospitals. A total of 50 cases diagnosed with obstructed nonperforated cancer colon were randomly allocated into two groups; the first group included 25 cases who underwent the one-stage approach, and the second one included the remaining 25 cases who underwent the two-stage approach. Results: Although the two-staged approach showed an increase in operative time compared to the single-stage approach (174.88 vs. 163.84 min, respectively), that difference was statistically insignificant (P 1⁄4 0.102). Hospital stay showed significant prolongation in the single-stage group (5.8 vs. 3.88 days in the two-stage group e P < 0.001). No significant difference was detected between the study groups regarding postoperative complications. Mortality was encountered only in one case in the one-stage group (4%) due to pulmonary embolism. The prevalence of patient dissatisfaction was significantly higher in the two-stage group (48%) compared to the single-stage group (12%). Conclusion: We concluded no significant increase in perioperative morbidity or mortality rates in the one-stage procedure compared to the staged one when applied for obstructed cancer colon patients.
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一期手术与两期手术治疗梗阻性非穿孔结肠癌
背景:肠急症患者的手术治疗仍有争议。然而,有越来越多的倾向于原发性重建手术。目的:在手术时间、住院时间、术后并发症、围手术期死亡率和生活质量方面,评估梗阻性非穿孔结肠癌患者一期手术与二期手术的差异。患者和方法:在曼苏拉大学急诊医院进行了一项前瞻性随机研究。50例诊断为梗阻性非穿孔结肠癌的患者随机分为两组;第一组25例采用一期入路,第二组25例采用两期入路。结果:虽然两阶段入路手术时间较单阶段入路增加(分别为174.88 min和163.84 min),但差异无统计学意义(P < 1 / 4 0.102)。单阶段组住院时间明显延长(5.8天vs. 3.88天,两阶段组P < 0.001)。在术后并发症方面,研究组之间没有发现显著差异。在一期组中只有一例(4%)因肺栓塞而死亡。患者不满意的发生率在两阶段组(48%)明显高于单阶段组(12%)。结论:与一期手术相比,一期手术治疗梗阻性结肠癌患者围手术期的发病率和死亡率没有显著增加。
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