Nodular cutaneous mucinosis--an unusual multiple type of euthyreotic focal mucinosis.

Dermatologica Pub Date : 1991-01-01 DOI:10.1159/000247643
B. Schneider, D. Hohl, U. Schnyder
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引用次数: 16

Abstract

A 32-year-old Turkish man with a progressive appearance of indolent, skin-colored nodules on the trunk and proximal extremities is presented. Clinical and laboratory examinations did not reveal any other relevant abnormalities. Histological specimens showed focal, ill-defined depositions of acid mucopolysaccharides mainly in the reticular dermis. Collagen fibers were split up and separated. Ultrastructurally, activated fibroblasts and an increased synthesis of collagen fibrils and elastic microfibrils as well as numerous macrophages were noticed. Diagnostically, an unusual multiple type of cutaneous focal mucinosis is most likely.
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结节性皮肤黏液病——一种罕见的多发性甲状腺增生局灶性黏液病。
一位32岁的土耳其男子,其躯干和四肢近端出现渐进性的皮肤色结节。临床和实验室检查未发现任何其他相关异常。组织学标本显示局灶性、不明确的酸性粘多糖沉积,主要在网状真皮中。胶原纤维被分解和分离。超微结构上可见成纤维细胞活化,胶原原纤维和弹性微原纤维合成增加,巨噬细胞增多。诊断上,一种不寻常的多种类型的皮肤局灶性黏液病是最有可能的。
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[RETICULOSARCOMA]. [Infectious diseases]. Linear pemphigus vulgaris along a surgical scar. Eccrine porocarcinoma. Elevated glucocorticoid receptor concentrations before and after glucocorticoid therapy in peripheral mononuclear leukocytes of patients with atopic dermatitis.
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