Body mass index – from the position of assessment of the condition of patients with ischemic heart disease

G. Nagaeva, M. Zhuraliev, N. P. Yuldoshev, V. Li, K. A. Olimov
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Abstract

Purpose: comparative analysis of clinical, laboratory and angiographic parameters in patients with coronary artery disease, depending on the level of body mass index (BMI).Material and Methods: 71 patients with coronary artery disease were examined. All underwent general clinical laboratory functional studies and coronary angiography with stenting of the coronary arteries. Depending on the level of BMI, 2 groups of patients were identified: 1 gr. – 36 patients with BMI < 30 kg/m2 and 2 gr. – 35 patients with BMI ³ 30 kg/m2.Results: an increase in BMI was associated with young age and female sex, but fewer acute forms of coronary artery disease. The level of BMI ³ 30 kg/m2 was characterized by greater comorbidity, with AH being more frequent among comorbidities; diabetes; diseases of the gastroduodenal zone GDZ (p < 0,05); COPD and past history of Covid-19. In addition, among patients with a BMI ³ 30 kg/m2, the incidence of complex ventricular cardiac arrhythmias was 4 times higher than in patients with a BMI < 30 kg/m2. In patients with BMI ³ 30 kg/m2, the average amount of medications taken per day was 0,8 less than in the comparison group. The most frequently taken groups of drugs (in addition to BAB and ASA drugs) among patients in group 2 were: calcium antagonists AK; sartans and hypoglycemic drugs, and among patients of group 1 – ACE inhibitors; statins; thienopyridines and antiarrhythmics. 8,5% of the surveyed were NOT adherent to drug treatment, while among patients in group 1 – 13,9% and in group 2 – 2,8% of respondents. An increase in BMI according to ECG data was characterized by an increase in heart rate and a greater predisposition to ventricular arrhythmia, and according to echocardiography, by a thickening of the LV walls and a decrease in its systolic function. Angiographically, higher BMI values were not a criterion for the complexity of vascular lesions. Nevertheless, the length of the atherosclerotic lesion in the respondents in group 2 was greater than in group 1 (p > 0,05). In patients with BMI ³ 30 kg/m2, lesions of the distal segments of the main coronary arteries were recorded comparatively more often, with type B stenosis prevailing in the PNA basin (60,0%); in the RCA basin – type A (31,6%) and type B (47,4%) stenoses.Conclusion: there are still many controversial points in the assessment of the relationship between excess weight and cardiovascular pathology. Nevertheless, the significance of the BMI indicator has its prerogatives in this direction, especially in primary health care at the first contact with a patient.
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体质指数——从体位评价缺血性心脏病患者的病情
目的:比较分析冠状动脉疾病患者的临床、实验室和血管造影参数与身体质量指数(BMI)水平的关系。材料与方法:对71例冠心病患者进行检查。所有患者都接受了一般的临床实验室功能检查和冠状动脉支架造影术。根据BMI水平,将患者分为两组:BMI < 30 kg/m2的患者分为1组- 36例,BMI³30 kg/m2的患者分为2组- 35例。结果:BMI的增加与年轻和女性有关,但较少出现急性冠状动脉疾病。BMI³30 kg/m2水平具有较高的合并症,AH在合并症中更为常见;糖尿病;胃十二指肠区GDZ病变(p < 0.05);慢性阻塞性肺病和过去的Covid-19病史。此外,BMI³30 kg/m2的患者中,复杂室性心律失常的发生率比BMI < 30 kg/m2的患者高4倍。BMI³为30 kg/m2的患者,平均每天服药量比对照组少0.8。2组患者除BAB和ASA药物外,最常服用的药物组为:钙拮抗剂AK;沙坦类药物和降糖药,以及1组- ACE抑制剂患者;他汀类药物;噻吩吡啶类药物和抗心律失常药物。接受调查的患者中有8.5%没有坚持药物治疗,而在第1组患者中有13.9%和第2组患者中有2.8%。根据心电图数据,BMI增加的特点是心率增加,更容易发生室性心律失常,根据超声心动图,左室壁增厚,收缩功能下降。在血管造影中,较高的BMI值并不是血管病变复杂程度的标准。然而,2组应答者动脉粥样硬化病变的长度大于1组(p > 0.05)。在BMI³30 kg/m2的患者中,冠状动脉主干远段病变的记录相对较多,PNA盆区以B型狭窄为主(60.0%);在RCA盆地- A型(31.6%)和B型(47.4%)狭窄。结论:超重与心血管病理关系的评价仍存在许多争议点。然而,BMI指标在这方面有其优势,特别是在初次接触病人的初级卫生保健方面。
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