Baxter Expands its Oncology Pipeline by Licensing European Rights to Onconova Therapeutics’ Rigosertib

Heather Cartwright
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Abstract

In return for US$50 M upfront and up to US$515 M in precommercialisation milestone payments, Baxter International has licensed European commercialisation rights to Onconova Therapeutics’ lead anticancer therapy rigosertib. The drug candidate is currently in Phase III development for myelodysplastic syndromes, for which it has been granted Orphan Drug Designation in the US and Europe, and is the subject of a Phase II/III study in pancreatic cancer. Baxter, which has an existing US$50 M equity position in Onconova, also has the option to develop rigosertib in additional indications.
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百特通过授权Onconova Therapeutics的Rigosertib的欧洲权利扩大其肿瘤产品线
为了回报5000万美元的预付款和高达5.15亿美元的商业化前里程碑付款,百特国际获得了Onconova Therapeutics的主要抗癌药物rigosertib的欧洲商业化权利。该候选药物目前处于骨髓增生异常综合征的III期开发阶段,已在美国和欧洲获得孤儿药认定,并正在进行胰腺癌的II/III期研究。百特目前在Onconova拥有5000万美元的股权,该公司还可以选择在其他适应症中开发rigosertib。
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