Zinc phosphide (rodenticide) poisoning: A case report of deliberate self-harm in an eleven-year-old

A. Adepoju, A. Asinobi, A. Ademola, O. Akinyinka, Olutosin Abioye, Adesola O. Adelaja, Philip O Robert
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Abstract

Zinc Phosphide(Zn3P2) is a common rodenticide freely available in Nigeria for use against rodents. Occasionally human consumption occurs either accidentally or intentionally with potential consequences of multiorgan toxicity and death. An 11-year-old boy consumed an unknown quantity of zinc phosphide marketed as Push Out® with the intention of committing suicide and killing some members of the family as his response to chastisement for a misdemeanour. Patient presented in the hospital 4 days after ingestion of zinc phosphide with a history of profound vomiting and abdominal pain. Laboratory evaluation showed evidence of hepatic dysfunction, acute kidney injury and elevated serum amylase. He was managed conservatively and discharged home after two weeks of admission. We report this case to emphasise the need for Paediatricians to consider ingestion of rodenticides as a differential diagnosis of hepatoxicity and pancreatic enzyme elevation, as well as to highlight the possibility of suicide among children. There is need to control the indiscriminate use of rodenticides, strengthen public health education on poisoning as well as establish Poison Information Centres in our environment.
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磷化锌(灭鼠剂)中毒:11岁儿童故意自残一例报告
磷化锌(Zn3P2)是一种常见的杀鼠剂,在尼日利亚可以免费获得,用于对付啮齿动物。人类偶尔会无意或有意地食用,可能导致多器官中毒和死亡。一名11岁男孩因轻罪受到惩罚,服用了数量不详的以Push Out®产品销售的磷化锌,意图自杀并杀死一些家庭成员。患者在摄入磷化锌4天后入院,有严重呕吐和腹痛史。实验室检查显示肝功能障碍、急性肾损伤和血清淀粉酶升高。他接受了保守治疗,两周后出院。我们报告这个病例是为了强调儿科医生需要考虑摄入灭鼠剂作为肝毒性和胰酶升高的鉴别诊断,以及强调儿童自杀的可能性。有必要控制滥用灭鼠剂,加强有关中毒的公众健康教育,并在我们的环境中建立中毒信息中心。
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