Infectious Disease Modeling: Creating a Community to Respond to Biological Threats

J. Kaufman, S. Edlund, Judith V. Douglas
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引用次数: 11

Abstract

The rise of global economies in the 21st century, the rapid national and international movement of people, and the increased reliance of developed countries on global trade, all greatly increase the potential and possible magnitude of a worldwide pandemic. New epidemics may be the result of global climate change, vector-borne diseases, food-borne illness, new naturally occurring pathogens, or bio-terrorist attacks. The threat is most severe for highly communicable diseases. When rapidly spreading microparasitic infections coincide with the rapid transportation, propagation, and dissemination of the pathogens and vectors for infection, the risks associated with emerging infectious disease increase. We discuss the use of publicly-available technologies in assisting public health officials and scientists in protecting populations from emerging disease or in implementing improved response measures. We illustrate possibilities using the SpatioTemporal Epidemiological Modeler (STEM) that was developed to run on the Open Health Framework (OHF) created by the Eclipse Foundation in 2004. An illustration regarding the spread of the influenza H1N1 virus from Mexico to the United States via air travel in Spring 2009 is briefly discussed.
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传染病建模:创建社区以应对生物威胁
21世纪全球经济的崛起、人口在国内和国际间的迅速流动以及发达国家对全球贸易的日益依赖,都大大增加了全球大流行病的可能性和可能的严重程度。新的流行病可能是全球气候变化、媒介传播疾病、食源性疾病、新的自然发生的病原体或生物恐怖袭击的结果。高度传染性疾病的威胁最为严重。当迅速蔓延的微寄生虫感染与病原体和感染媒介的快速运输、繁殖和传播同时发生时,与新发传染病相关的风险就会增加。我们讨论利用公开技术协助公共卫生官员和科学家保护民众免受新出现疾病的侵害或实施改进的应对措施。我们使用时空流行病学建模器(STEM)来说明可能性,该模型是为运行在Eclipse基金会于2004年创建的开放健康框架(OHF)上而开发的。本文简要讨论了2009年春季H1N1流感病毒通过航空旅行从墨西哥传播到美国的情况。
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