Research Progress in the Repair of Peripheral Nerve Injury with Adipose-Derived Stem Cell Exosomes

Xinyu Ben, Hui-hui Zheng, Ya-Ru Wang, Fangfang Liu, Qingyi Zhu, Rui Ren, Xinan Yi
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Abstract

The repair of peripheral nerve injury has always been a difficult clinical problem. Although a variety of treatment methods are available in clinical practice, their efficacy is limited. In recent years, the components carried by adipose stem cell exosomes and their functions have been increasingly discovered. A large number of experiments conducted around the world have shown that adipose-derived stem cell exosomes have a positive effect on the repair of peripheral nerve injury. This article reviews recent progress toward the use of adipose-derived stem cell exosomes in the repair of injured peripheral nerves and possible future research directions involving adipose-derived stem cell exosomes.
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脂肪来源干细胞外泌体修复周围神经损伤的研究进展
周围神经损伤的修复一直是临床难题。虽然临床上有多种治疗方法,但其疗效有限。近年来,脂肪干细胞外泌体所携带的成分及其功能被越来越多地发现。世界各地进行的大量实验表明,脂肪来源的干细胞外泌体对周围神经损伤的修复具有积极作用。本文综述了近年来利用脂肪源性干细胞外泌体修复周围神经损伤的研究进展,以及脂肪源性干细胞外泌体未来可能的研究方向。
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