Research Progress on the Relationship between BDNF, the Polymorphysis of Its Gene, and Childhood Autism

Abstract

Studies have shown that the expression level of the brain-derived neurotrophic factor (also known as BDNF) is of great significance on neutron activity, which has a close relationship with the improvement of the learning and memory ability; it has effect on the physical growth and development of an individual as well. On the other hand, childhood autism is a group of serious neurodevelopmental disorders. Some literature has pointed out that the BDNF plays a tremendously important role in the pathogenesis and the treatment of neuropsychiatric diseases. In recent years, many scholars at home and abroad have done a lot of research and found that there is a close relationship between BDNF and autism. This paper therefore will give an introduction on and an analysis of the relationship between BDNF, the polymorphysis of its gene, and childhood autism based on the previous domestic and overseas literature.