Surveillance of D'Aguilar Virus in Kyoto Prefecture

Naoki Kubota, Takuhiro Kira, T. Yanase
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Abstract

SUMMARY D ʼ Aguilar virus (DAGV) that is an arthropod-borne virus suspected of being involved in bovine abnormal births, has been confirmed the domestic spread of infection mainly in the Kyushu-Okinawa region. Serological surveillance of DAGV was conducted using serum samples collected from 498 sentinel cattle in Kyoto Prefecture between 2005 and 2018. Neutralization antibodies against DAGV were detected in 17 cattle tested in 2013, 2017, and 2018. A DAGV-specific gene was amplified from the blood samples of 10 seropositive cattle tested in 2017 and 2018, and the virus was isolated from four of them that were collected in 2017. In Japan, this is the first detection of DAGV outside of the Kyushu-Okinawa region.
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京都县D'Aguilar病毒监测
阿吉拉病毒(DAGV)是一种节肢动物传播的病毒,怀疑与牛异常分娩有关,已确认主要在九州-冲绳地区传播。利用2005年至2018年从京都县498头哨岗牛采集的血清样本对DAGV进行了血清学监测。在2013年、2017年和2018年测试的17头牛中检测到针对DAGV的中和抗体。从2017年和2018年检测的10头血清阳性牛的血液样本中扩增出dagv特异性基因,并从2017年收集的4头牛中分离出该病毒。在日本,这是九州-冲绳地区以外首次检测到DAGV。
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