Phytochemical Constituents of Three Species of Marine Macro- Algae from Sitio Usadda, Pangutaran, Sulu, Philippines

M. Hanani
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引用次数: 1

Abstract

Seaweeds are a rich source of highly potential bioactive compounds in the pharmaceutical industry. To date, many chemically unique compounds of marine origin with various biological activities have been isolated and some of them are under investigation and to develop new pharmaceuticals. The phytochemical screening will be limited to the determination of alkaloids, flavonoids, saponins, tannins and terpenoids using two organic solvents such as ethanol and methanol. The result of the phytochemical test proves that there is a difference in the capacity of different solvents to extract active compounds. In methanol extracts tannins and terpenoids are present in Ulva reticulate in moderate amount. Terpenoids are slightly present in Sargassum cristaefolium and terpenoids and saponins are slightly present in Halymenia durvillei. In methanol extracts Ulva reticulata contains coumarins and saponins in moderate amount and terpenoids is only slightly present. Also, the methanol extract of Sargassum cristaefolium and Halymenia durvillei, contain terpenoids in moderate amount. It can be deduced from the screening test that terpenoids is the dominant constituents present in the three algal samples. Both ethanol and methanol seaweed extracts showed that alkaloids, flavonoids and xanthoprotein were absent in the three seaweed extracts of U. reticulata, S. cristaefolium and H. durvillei. An absence of alkaloid in U. reticulata in present study is due to effect of the geographical location and seasons of collection. Differences can be attributed to solubility of active component in different solvents used. Methods of extraction were possible sources of variation for chemical composition and extracted for bioactivity reaction. Indeed, there is no doubt that more terpenoids identified from marine algae will become available and will be used in food industry and will be utilized as source of natural antioxidant and clinical drugs that will play a significant role in human disease treatment in the future.
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菲律宾苏禄庞古塔兰岛Sitio Usadda三种海洋大型藻类的植物化学成分
海藻是制药工业中极具潜力的生物活性化合物的丰富来源。迄今为止,许多具有各种生物活性的海洋来源的化学独特化合物已被分离出来,其中一些正在研究和开发新的药物。植物化学筛选将仅限于使用乙醇和甲醇两种有机溶剂测定生物碱、黄酮类、皂苷、单宁和萜类。植物化学试验结果证明,不同溶剂提取活性化合物的能力是不同的。甲醇提取物中单宁和萜类化合物的含量适中。马尾草中有少量萜类化合物,杜鹃中有少量萜类化合物和皂苷。甲醇提取物中含有适量香豆素和皂甙,萜类仅少量存在。马尾草和杜鹃的甲醇提取物中含有适量的萜类化合物。从筛选试验可以推断,萜类化合物是三种藻类样品中存在的优势成分。海藻乙醇和甲醇提取物均不含生物碱、黄酮类化合物和黄质蛋白。由于地理位置和采收季节的影响,本研究中网状藤中生物碱的缺失。差异可归因于活性成分在不同溶剂中的溶解度。提取方法是化学成分变化的可能来源,也是提取生物活性反应的可能来源。事实上,毫无疑问,从海藻中发现的更多萜类化合物将被用于食品工业,并将作为天然抗氧化剂和临床药物的来源,在未来的人类疾病治疗中发挥重要作用。
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