The Influence of Several Biological Parameters on the Management of Patients with Colon Cancer Undergoing Elective Surgery

C. V. I. Feier, Andra Olariu, Sorin Olariu
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引用次数: 1

Abstract

(1) Aim of the study: Our study aims to analyze the influence of biological parameters such as hemoglobin, albumin, total protein, on the management and duration of treatment of colon cancer patients who have undergone elective surgery. (2) Material and methods: Data of 147 patients from the Surgery Clinic 1 of the County Clinical Hospital of Timisoara who underwent an elective surgery for colon cancer treatment were statistically analyzed using statistical tests such as Anova or Chi square with a p < 0.05 considered to be statistically significant. (3) Results: Differences between preoperative and postoperative parameters were correlated with the duration of surgery (hemoglobin, p = 0.014). The average length of hospital stay was correlated with the difference between the preoperative and postoperative level of hemoglobin (p = 0.043). There was a direct correlation between the length of postoperative hospital stay and the difference between the plasmatic levels of albumin (p = 0.033). There were differences in the average Charlson index value of patients who required albumin, with no statistical significance. (4) Conclusions: The difference between preoperative and postoperative levels of biological parameters (hemoglobin, albumin, total protein) has an influence on the management of patients with colon cancer undergoing elective surgery, affecting the number of days the patients spend in the hospital after the surgical procedure, as well as the total number of days spent in the hospital (from day one to discharge). The greater the variation of those differences, the longer recovery period needed, showing that an early correction of those parameters can lead to a shorter hospital stay, a faster postoperative recovery and a shorter postoperative hospital stay.
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若干生物学参数对结肠癌择期手术患者处理的影响
(1)研究目的:本研究旨在分析血红蛋白、白蛋白、总蛋白等生物学参数对择期手术结肠癌患者管理及治疗时间的影响。(2)材料与方法:对蒂米什瓦拉县临床医院外科1诊所择期行结肠癌手术治疗的147例患者资料进行统计学分析,采用方差分析或卡方等统计学检验,p < 0.05为有统计学意义。(3)结果:术前、术后参数差异与手术时间相关(血红蛋白,p = 0.014)。平均住院时间与术前术后血红蛋白水平差异相关(p = 0.043)。术后住院时间与血浆白蛋白水平差异有直接相关性(p = 0.033)。需用白蛋白患者的平均Charlson指数值差异无统计学意义。(4)结论:术前、术后生物参数(血红蛋白、白蛋白、总蛋白)水平的差异对择期手术结肠癌患者的管理有影响,影响患者术后住院天数,以及住院总天数(从第一天到出院)。这些差异的差异越大,所需的恢复期就越长,这表明及早纠正这些参数可以缩短住院时间,加快术后恢复,缩短术后住院时间。
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审稿时长
6 weeks
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