Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes

A. Jacob, J. Paul, S. Rajan, G. Ravindran, L. Kumar
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Abstract

Background and Aims: Spinal anesthesia is a technique widely used for gynecological, lower abdominal, pelvic and lower limb procedures. Even though it causes a profound nerve block, it is associated with profound hypotension. Aims of the Study: To assess the effect of the speed of injection of heavy bupivacaine on quality of block and hemodynamic changes in patients undergoing gynecological surgeries under spinal anesthesia. Methods: This was a prospective randomized study conducted on 40 patients. Group F patients were given 3.2 mL of 0.5% heavy bupivacaine intrathecally in 15 s and Group S patients were given the same drug over 60 s. The time to achieve T10 dermatomal block, maximum block height, block height at 5 min were recorded. Heart rate (HR), systolic, diastolic blood pressures, and mean arterial pressures (MAP) were also recorded at different time points. Results: HR, systolic BP, diastolic BP, and MAPs and mean block height at 5 min were comparable between the two groups at all time points. The time to achieve T10 dermatome block was significantly faster in Group F (1.85 ± 1.14 min) as compared to Group S (3.98 ± 1.58 min). Majority of patients in Group F (65%) had a maximum block up to T6 and those in Group S (45%) had a block upto T4. The usage of vasopressors was found to be significantly higher in Group F compared to Group S with P = 0.041. Conclusion: Using faster speed of injection of heavy bupivacaine during spinal anesthesia can lead to faster achievement of blockade but with significantly higher usage of vasopressors.
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大剂量布比卡因注射速度对阻滞质量和血流动力学变化的影响
背景和目的:脊髓麻醉是一种广泛应用于妇科、下腹部、骨盆和下肢手术的技术。即使它引起深度神经阻滞,它也与深度低血压有关。研究目的:评价重剂量布比卡因注射速度对脊柱麻醉下妇科手术患者阻滞质量和血流动力学变化的影响。方法:对40例患者进行前瞻性随机研究。F组患者15 s内滴注0.5%重布比卡因3.2 mL, s组患者60 s内滴注相同药物。记录皮节阻滞达到T10的时间、最大阻滞高度、5 min时的阻滞高度。在不同时间点记录心率(HR)、收缩压、舒张压和平均动脉压(MAP)。结果:两组在所有时间点的HR、收缩压、舒张压、map和平均阻滞高度均具有可比性。F组达到T10皮区阻滞的时间(1.85±1.14 min)明显快于S组(3.98±1.58 min)。F组大多数患者(65%)最大阻滞至T6, S组患者(45%)阻滞至T4。F组血管加压药物的使用明显高于S组,P = 0.041。结论:腰麻时采用更快的重布比卡因注射速度可更快达到阻滞,但血管加压剂的使用率明显增加。
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