Meta-analysis of prevalence in Chinese civil aviation pilots

中华航空航天医学杂志 Pub Date : 2017-03-15 DOI:10.3760/CMA.J.ISSN.1007-6239.2017.01.013

Yi-qing Yang, L. Pan, Jian Gao, Xiaorong Liu

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Abstract

Objective To evaluate and analyze the prevalence of various diseases in Chinese civil aviation pilots, and to provide the basis of improving the fitness of pilots. Methods The information of physical examinations of civil aviation pilots up to June of 2016 was extracted from the literatures included by CBM, China Journal Fulltext Database, China Scientific Journal Database and Wanfang Data. Open Meta [Analyst] software was used to incorporate the single rate and the outcomes were expressed as prevalence and 95% CI, and to analyze the subgroups according to different characteristics of pilots. STATA software was used for publication bias. Results Twenty-six literatures were included for meta-analysis and 122 424 persons involved (aging from 16 to 73 yr). The diseases were mainly cardiovascular diseases, liver diseases, eye diseases and abnormal blood biochemical indexes. The Meta-analysis showed that the prevalence of various diseases in Chinese civil aviation pilots were: hypertension 9.2% (95% CI was 7.1%-11.4%, I2=98%), overweight and obesity 42.2% (95% CI was 29.0%-55.5%, I2=100%), dyslipidemia 38.2% (95% CI was 24.1%-52.4%, I2=100%), in which the prevalence of TG was 28.0% (I2=98%), TC was 19.9% (I2=99%), HDL-C was 23.4% (I2=97%), and LDL-C was 19.3% (I2=98%). The prevalence of hyperglycemia and hyperuricemia was respectively 3.1% (95% CI was 0.7%-5.6%, I2=95%) and 22.6% (95% CI was 18.5%-26.6%, I2=79%). The prevalence of fatty liver and gallbladder polyp was respectively 20.2% (95% CI was 10.4%-30.0%, I2=98%) and 5.2% (95% CI was 4.7%-5.8%, I2=0%). The prevalence of cataracts and poor vision was respectively 0.2% (95% CI was 0.1%-0.3%, I2=80%) and 9.4% (95% CI was 9.0%-9.7%, I2=0%). 10.2% pilots were diagnosed as hearing loss (I2=54%). Pilots at different age had different prevalence of hypertension. Conclusions The high incidences of overweight/obesity, dyslipidemia, hyperuricemia, fatty liver and hypertension are found in Chinese civil aviation pilots, and these suggest the importance of countermeasures for improving their healthiness. Key words: Physical examination; Prevalence rate; Meta-analysis; Pilots

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中国民航飞行员患病率的meta分析

目的了解和分析我国民航飞行员各种疾病的流行情况，为提高飞行员的健康水平提供依据。方法提取CBM、中国期刊全文数据库、中国科学期刊数据库和万方数据库收录的截至2016年6月的民航飞行员体检信息。使用Open Meta [Analyst]软件合并单一发生率，结果以患病率和95% CI表示，并根据飞行员的不同特征分析亚组。发表偏倚采用STATA软件。结果纳入26篇文献进行meta分析，涉及122424人(年龄16 ~ 73岁)。疾病主要为心血管疾病、肝病、眼病和血液生化指标异常。meta分析显示，中国民航飞行员各类疾病患病率为:高血压9.2% (95% CI为7.1% ~ 11.4%，I2=98%)，超重和肥胖42.2% (95% CI为29.0% ~ 55.5%，I2=100%)，血脂异常38.2% (95% CI为24.1% ~ 52.4%，I2=100%)，其中TG患病率为28.0% (I2=98%)， TC患病率为19.9% (I2=99%)， HDL-C患病率为23.4% (I2=97%)， LDL-C患病率为19.3% (I2=98%)。高血糖和高尿酸血症的患病率分别为3.1% (95% CI为0.7% ~ 5.6%，I2=95%)和22.6% (95% CI为18.5% ~ 26.6%，I2=79%)。脂肪肝和胆囊息肉患病率分别为20.2% (95% CI为10.4% ~ 30.0%，I2=98%)和5.2% (95% CI为4.7% ~ 5.8%，I2=0%)。白内障和视力不良的患病率分别为0.2% (95% CI为0.1% ~ 0.3%，I2=80%)和9.4% (95% CI为9.0% ~ 9.7%，I2=0%)。10.2%的飞行员被诊断为听力损失(I2=54%)。不同年龄的飞行员高血压患病率不同。结论我国民航飞行员超重/肥胖、血脂异常、高尿酸血症、脂肪肝和高血压的发生率较高，应采取相应的措施改善其健康状况。关键词:体检;流行率;荟萃分析;飞行员

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中华航空航天医学杂志航空航天医学

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2962

期刊介绍： The aim of Chinese Journal of Aerospace Medicine is to combine theory and practice, improve and popularize, actively advocate a hundred flowers bloom and a hundred schools of thought contend, advocate seeking truth from facts, promote the development of the related disciplines of aerospace medicine and human efficiency, and promote the exchange and penetration of aerospace medicine and human efficiency with other biomedical and engineering specialties. Topics of interest for Chinese Journal of Aerospace Medicine include: -The content of the journal belongs to the discipline of special medicine and military medicine, with the characteristics of multidisciplinary synthesis and cross-penetration, and mainly reflected in the aerospace industry, aerospace flight safety and efficiency, as well as the synthesis of special medicine, preventive medicine, environmental medicine, psychology, etc. -Military aeromedicine (Air Force, Navy and Army aeromedicine) and civil aeromedicine, with a balance of aerospace medicine are the strengths of the journal. -The change in aerospace medicine from a focus on promoting physiological compensatory adaptations to enhancing human performance under extreme environmental conditions is what the journal is helping to promote. -The expansion of manuscripts in high altitude medicine is also a special emphasis of the journal.