A Comparative Study on Antioxidant Activity of Infusion and Decoction of (Cayratia trifolia (L.) Domin)

IF 2.9 4区 医学 Q2 PHARMACOLOGY & PHARMACY Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2023-07-11 DOI:10.36490/journal-jps.com.v6i3.55
Angel Mangiwa, Mirna Maulidah, Tipalmaton R Patulen, Dhea K Kende, I. Ismail, Desy A Lestari, Maulita Indrisari, L. Muslimin
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Abstract

The number of patients with neurodegenerative disorders increased, especially in the productive age. The neurodegenerative disorder can be prevented by synthetic and natural antioxidants such as from plants. The herb of galling, Cayratia trifolia (L.) Domin), has long been traditionally used to prevent degenerative diseases by drinking decoction. The current study aimed to compare the antioxidant capability between infusion and decoction of galling against DPPH. The herbs were extracted with two methods, namely infusion, and decoction. This study used 7 different serial concentrations ranging 7.81 till 500 µg/mL, while the optical density was recorded at 515 nm using a spectrophotometer. The results demostrated that both infusion and decoction have antioxidant activity against DPPH with IC50 values of 87.55±1.01 (strong category) and 65.38±2.26 µg/mL (strong category), respectively. There was a statistically significant (p<0.05) between the IC50 values of infusion and decoction. In conclusion, galling is efficacious as an antioxidant source for preventing and treating degenerative diseases.
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三叶草浸提液与煎提液抗氧化活性的比较研究多明)
神经退行性疾病患者的数量增加,特别是在生产年龄。神经退行性疾病可以通过合成和天然抗氧化剂(如来自植物的抗氧化剂)来预防。刺蒺藜的草本植物,三叶蒺藜(L.)长期以来,传统上通过饮用汤剂来预防退行性疾病。本研究的目的是比较胆灼液和胆灼液对DPPH的抗氧化能力。采用浸提和煎提两种方法提取。本研究采用7.81 ~ 500µg/mL 7种不同的连续浓度,在515 nm处用分光光度计记录光密度。结果表明,冲剂和煎剂均具有抗DPPH活性,IC50值分别为87.55±1.01µg/mL(强类)和65.38±2.26µg/mL(强类)。冲剂与煎剂的IC50值比较,差异有统计学意义(p<0.05)。总之,胆汁作为一种抗氧化来源,对预防和治疗退行性疾病是有效的。
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来源期刊
CiteScore
6.90
自引率
0.00%
发文量
29
审稿时长
6-12 weeks
期刊介绍: The Journal of Pharmacy and Pharmaceutical Sciences (JPPS) is the official journal of the Canadian Society for Pharmaceutical Sciences. JPPS is a broad-spectrum, peer-reviewed, international pharmaceutical journal circulated electronically via the World Wide Web. Subscription to JPPS is free of charge. Articles will appear individually as soon as they are accepted and are ready for circulation.
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