Cohort study of the overall survival of patients with pancreatic cancer in a hospital of specialties of Quito-Ecuador in the period 2007–2017

IF 1.7 Q2 SURGERY Innovative Surgical Sciences Pub Date : 2021-05-03 DOI:10.1515/iss-2020-0030
Andrés Moreno Roca, L. Armijos Acurio, R. Jimbo Sotomayor, Carlos Céspedes Rivadeneira, Carlos Rosero Reyes, Carlos López Ayala
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引用次数: 1

Abstract

Abstract Objectives Pancreatic cancers in most patients in Ecuador are diagnosed at an advanced stage of the disease, which is associated with lower survival. To determine the characteristics and global survival of pancreatic cancer patients in a social security hospital in Ecuador between 2007 and 2017. Methods A retrospective cohort study and a survival analysis were performed using all the available data in the electronic clinical records of patients with a diagnosis of pancreatic cancer in a Hospital of Specialties of Quito-Ecuador between 2007 and 2017. The included patients were those coded according to the ICD 10 between C25.0 and C25.9. Our univariate analysis calculated frequencies, measures of central tendency and dispersion. Through the Kaplan-Meier method we estimated the median time of survival and analyzed the difference in survival time among the different categories of our included variables. These differences were shown through the log rank test. Results A total of 357 patients diagnosed with pancreatic cancer between 2007 and 2017 were included in the study. More than two-thirds (69.9%) of the patients were diagnosed in late stages of the disease. The median survival time for all patients was of 4 months (P25: 2, P75: 8). Conclusions The statistically significant difference of survival time between types of treatment is the most relevant finding in this study, when comparing to all other types of treatments.
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基多-厄瓜多尔某专科医院2007-2017年胰腺癌患者总生存期的队列研究
在厄瓜多尔,大多数胰腺癌患者被诊断为胰腺癌晚期,这与较低的生存率相关。确定2007年至2017年厄瓜多尔一家社会保障医院胰腺癌患者的特征和总体生存率。方法利用基多-厄瓜多尔一家专科医院2007年至2017年诊断为胰腺癌的患者的电子临床记录中所有可获得的数据进行回顾性队列研究和生存分析。纳入的患者是根据ICD 10在C25.0到C25.9之间进行编码的患者。我们的单变量分析计算了频率、集中趋势和分散的度量。通过Kaplan-Meier法估计中位生存时间,并分析不同类别纳入变量的生存时间差异。这些差异是通过对数秩检验来显示的。结果在2007年至2017年期间,共有357名诊断为胰腺癌的患者被纳入研究。超过三分之二(69.9%)的患者被诊断为疾病晚期。所有患者的中位生存时间均为4个月(P25: 2, P75: 8)。结论与所有其他治疗方式相比,不同治疗方式的生存时间差异具有统计学意义,这是本研究中最相关的发现。
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来源期刊
CiteScore
5.40
自引率
0.00%
发文量
29
审稿时长
11 weeks
期刊最新文献
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