Efficacy of herbal products as denture cleansers - An in vitro study

Abstract

The Journal of Indian Prosthodontic Society | Volume 20 | Supplement 1 | December 2020 S9 Introduction: Patients with diabetes mellitus are more prone to develop candida infection. In such patients, the use of denture adhesive which is difficult to remove from the denture surface and oral mucosa is still questionable. The aim of the present randomized controlled crossover clinical study was to investigate the influence of paste and powder form of denture adhesives on the growth of candida albicans in denture wearing diabetic patients. The objectives of the study were to evaluate and compare the change in CFU/ml after the usage denture adhesives. Methodology: 20 participants with known diabetes were enrolled in the study after confirmatory HbA1C diagnostic test. They were randomly divided for the use of paste and powder forms of denture adhesives. Protocol A: Use of paste form of denture adhesive for 14 days followed by use of powder form of denture adhesive for another 14 days. Protocol B: Use of powder form of denture adhesive for 14 days followed by use of paste form of denture adhesive for another 14 days. Salivary samples were collected at three time intervals. Growth of candida albicans was assessed in the non-selective SDA medium after incubation for 48 hours. Result: Intra-group comparisons by Wilcoxon Ranked sum test suggested no statistical significant change for paste form of adhesive (p=0.129) and powder form of adhesive (p=0.336). Inter group comparison also suggested no significant difference between two adhesives (p=0.473). Conclusion: There was an insignificant increase in the numbers of salivary CFU/ml of candida albicans following the use of paste and powder form of denture adhesive in denture wearing diabetic patients. DOI: 10.4103/0972-4052.306363 Efficacy of herbal products as denture cleansers An in vitro study