The Cytotoxic Constitunets of Euphorbia Makinoi

J. Weng, H. Su, M. Yen, S. Won, Chun-nan Lin
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引用次数: 1

Abstract

One new triterpene, cycloart-24β-methoxy-3β-ol (1), and seven known com pounds, were isolated from the whole herb of Euphorbia makinoi. Their structures were established by spectral methods, and their cytotoxic activities were evaluated against three different cell lines. Com pound 1 showed marginal cytotoxic activity against the three human cancer cell lines while 3 showed marginal cytotoxic activity against Hep 3B and HT-29 cells in vitro.
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大戟的细胞毒性成分
从大戟(Euphorbia makinoi)全草中分离到1个新的三萜环亚酮-24β-甲氧基-3β-醇(1)和7个已知化合物。用光谱法确定了它们的结构,并对三种不同细胞系进行了细胞毒活性评价。compound 1对3种人类癌细胞系均表现出边缘性细胞毒活性,而3对Hep 3B和HT-29细胞均表现出边缘性细胞毒活性。
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