Classification Modelling: A Case Study of Breast Cancer Patients of Islamabad

Aansa Abbas, M. Zakria, Muhammad Kashif
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Abstract

Purpose: The rate of breast cancer in Pakistan is the highest among all other Asian countries and all other types of cancer. The foremost treatment for breast cancer patients of stage 2 and stage 3 is surgery. The main types of surgery in this era are Mastectomy and Breast Conservative surgery. The decision about the type of surgery depends on the demographic and clinical factors. Approach: In this study, the seven characteristics have been considered.  A purposive sample of 365 breast cancer patients were collected from the two main hospitals in Islamabad. The foremost objective of this study was to classify each breast cancer patient regarding surgery type based on significant explanatory characteristics. The binary logistics regression and discriminant analysis techniques were used and the significance of each parameter was tested. Findings: The main effects i.e., age, tumor size, Estrogen Receptor, and Progesterone Receptor were found to be significant with some diverse probabilities and all two-factor interactions were found to be non-significant. The sensitivity of logistic regression and discriminant analysis is almost the same i.e., 93.1% and 92.8% respectively whereas the specificity of these two techniques is also almost the same i.e., 70.8% and 71.9% respectively. The overall actual correct classify rate and Apparent error rate of both these techniques are found to be 87.7% and 12.3% respectively. Implications: In brief, it was deducted that the Tumor size stage is the most imperative characteristic among other significant characteristics in discriminating between two types of surgery
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分类建模:以伊斯兰堡乳腺癌患者为例
目的:在所有其他亚洲国家和所有其他类型的癌症中,巴基斯坦的乳腺癌发病率最高。对于2期和3期乳腺癌患者来说,最重要的治疗是手术。这个时代的主要手术类型是乳房切除术和乳房保守手术。手术类型的决定取决于人口统计学和临床因素。方法:在本研究中,考虑了七个特征。从伊斯兰堡的两家主要医院收集了365名乳腺癌患者的目的样本。本研究的首要目的是根据显著的解释特征对每个乳腺癌患者的手术类型进行分类。采用二元logistic回归和判别分析技术,对各参数的显著性进行检验。结果:年龄、肿瘤大小、雌激素受体、孕激素受体等主要影响因素具有不同概率的显著性,双因素相互作用均不显著。logistic回归和判别分析的敏感性基本相同,分别为93.1%和92.8%,特异性也基本相同,分别为70.8%和71.9%。两种方法的总体实际正确分类率和表观错误率分别为87.7%和12.3%。意义:简而言之,我们推断肿瘤大小分期是区分两种手术类型的最重要特征
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审稿时长
12 weeks
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