Esophagitis after Clozapine Use in a 61-Year-Old Woman with Refractory Schizophrenia

Q4 Medicine Case Reports in Psychiatry Pub Date : 2022-06-03 DOI:10.1155/2022/7033038
Sung Min Ma, J. Lim, Chunsu Jiang, Luminita Luca
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引用次数: 2

Abstract

Clozapine-induced esophagitis has been rarely reported. We herein report a case of a 61-year-old woman with schizophrenia who developed hematemesis, fever, and tachycardia after the initiation of clozapine. An esophagogastroduodenoscopy showed esophageal mucosal ulcerations. Her gastrointestinal symptoms resolved with pantoprazole, allowing continuation of her clozapine treatment. We report here an unusual association of severe esophagitis with clozapine use.
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氯氮平治疗61岁难治性精神分裂症后食管炎
氯氮平引起的食管炎很少有报道。我们在此报告一例61岁女性精神分裂症患者,在开始使用氯氮平后出现呕血、发热和心动过速。食管胃十二指肠镜检查显示食管黏膜溃疡。她的胃肠道症状在泮托拉唑治疗下得到缓解,允许继续氯氮平治疗。我们在此报告重度食管炎与氯氮平使用的不寻常关联。
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来源期刊
Case Reports in Psychiatry
Case Reports in Psychiatry Medicine-Psychiatry and Mental Health
CiteScore
1.00
自引率
0.00%
发文量
49
审稿时长
12 weeks
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