Neurogenic bladder dysfunction after total mesorectumectomy

E. G. Azimov, S. Aliyev
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Abstract

AIM: to estimate the rate, causes and features of neurogenic bladder dysfunction in patients with rectal cancer after total mesorectumectomy.PATIENTS AND METHODS: the results of surgical treatment of 103 patients with rectal cancer were analyzed in the light of immediate and long-term outcomes, who underwent total mesorectumectomy using traditional (56-54.4%) and laparoscopic (47-45.6%) technologies. In 20 (19.4%) of 103 patients, the course of the immediate postoperative period was complicated by the development of neurogenic bladder dysfunction. In order to study the frequency of neurogenic bladder dysfunction depending on the technique of mesorectumectomy, the patients were divided into 2 groups. Group 1 included 9 patients who underwent laparoscopic total mesorectumectomy. Group 2 included 11patients who underwent traditional (open) mesorectumectomy.RESULTS: the study of the functional state of the bladder according to the flowmetric indicators revealed that the frequency of development of postoperative bladder dysfunction has a gender dependence. The frequency of neurogenic bladder dysfunction was 25% in men and 10,7% in women. It is shown that during 1 week and 6 months after surgery, the average urination rate tends to increase in women and decrease in men, regardless of the technique of total mesorectumectomy. In both groups, there was not a statistically significant decrease in the maximum volumetric velocity in both men and women within 6 months after surgery. At the same time, during this period, there was a decrease in the average rate of urination only in men, regardless of the technique of total mesorectumectomy. And in women, this indicator remained unchanged or slightly increased.CONCLUSION: it is shown that a complex system of therapeutic measures, including drug stimulation of the detrusor and urethral sphincter, repeated catheterization of the bladder, as well as epicystostomy performed according to indications, allows adequate correction of bladder dysfunction after total mesorectumectomy in patients with rectal cancer.
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全肠系膜切除术后神经源性膀胱功能障碍
目的:了解直肠癌全肠系膜切除术后神经源性膀胱功能障碍的发生率、原因及特点。患者和方法:对103例采用传统(56-54.4%)和腹腔镜(47-45.6%)技术行全肠系膜切除术的直肠癌患者的近期和长期治疗结果进行分析。103例患者中有20例(19.4%)术后并发神经源性膀胱功能障碍。为了研究系直肠切除术后神经源性膀胱功能障碍的发生率,我们将患者分为两组。第一组包括9例行腹腔镜全肠系膜切除术的患者。第二组包括11例行传统(开放式)肠系膜切除术的患者。结果:根据流量指标对膀胱功能状态的研究发现,术后膀胱功能障碍的发生频率存在性别依赖性。神经源性膀胱功能障碍的发生率在男性中为25%,在女性中为10.7%。结果表明,在术后1周和6个月内,无论采用何种方法,女性的平均排尿率均有上升趋势,而男性则有下降趋势。在两组中,在术后6个月内,男性和女性的最大体积速度都没有统计学上的显著下降。与此同时,在此期间,无论采用全肠系膜切除术技术,只有男性的平均排尿率有所下降。在女性中,这一指标保持不变或略有增加。结论:通过药物刺激逼尿肌和尿道括约肌,反复置管膀胱,以及根据指征进行上睑造瘘等复杂的治疗措施,可以充分矫正直肠癌全肠系膜切除术后膀胱功能障碍。
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