Inhaled corticosteroid therapy in Asthma and Osteoporosis

Abstract

followed fluticasone propionate (n=2, 28.6%). One is on high dose budesonide (>800 µg/day), 1 medium dose budesonide (> 400-800µg/day), 3 low dose budesonide (200-400 µg/ day), 1 high dose fluticasone (>500µg/day) and 1 patient low dose fluticasone (100-250µg/day). Inhaled corticosteroids (ICS) are widely used in the treatment of asthma but their safety on bone density is controversial. 1 Bone mineral density (BMD) is assessed by DEXA - dual energy radiologic absorptiometry (osteodensitometry) - performed at the proximal femur and lumbar spine levels. The absolute BMD values and the T-score (femoral neck, total hip and lumbar spine) should be taken into account in postmenopausal women and in men over 50 years of age (T-score≥-1:normal; -2.5

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吸入皮质类固醇治疗哮喘和骨质疏松症

其次是丙酸氟替卡松(2例，28.6%)。1例患者服用高剂量布地奈德(>800µg/天)，1例中剂量布地奈德(> 400-800µg/天)，3例低剂量布地奈德(200-400µg/天)，1例高剂量氟替卡松(>500µg/天)和1例低剂量氟替卡松(100-250µg/天)。吸入性皮质类固醇(ICS)被广泛用于治疗哮喘，但其对骨密度的安全性存在争议。骨密度(BMD)通过DEXA -双能放射吸收仪(骨密度仪)评估-在股骨近端和腰椎水平进行。绝经后女性和50岁以上男性应考虑绝对骨密度值和t评分(股骨颈、全髋关节和腰椎)(t评分≥-1:正常;-2.5 < t指数< 1:骨量减少;t指数≤-2.5:骨质疏松症)。在绝经前

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