Cerebellum, GABA, and ataxia

Robert Lalonde, C. Strazielle
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Abstract

Various clinical results are obtained regarding the effects of cerebellar GABA transmission on spinocerebellar ataxias. Based on animal studies, it is proposed that balanced GABAergic transmission between GABA and other neurotransmitters such as glutamate may lead to more promising results in treating such conditions.
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小脑GABA传递对脊髓小脑共济失调的影响有不同的临床结果。在动物实验的基础上,我们提出GABA与谷氨酸等其他神经递质之间平衡的GABA能传递可能会导致治疗此类疾病的更有希望的结果。
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