Epidemiology, Diagnosis, and Treatment of Portal Vein Thrombosis

J. Seo, Se Hwa Kim, Yang Jae Yoo, Ah Young Lee, Sang Jong Park
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Abstract

In recent years, the incidence of portal vein thrombosis (PVT) in patients with cirrhosis has increased; the thrombosis ranges from asymptomatic partial to complete occlusion. Treatment is difficult. Anticoagulation therapy may be the optimal first-line treatment for patients with acute PVT who lack variceal bleeding or mesenteric ischemia. Minimally invasive treatment options include mechanical thrombectomy, chemical thrombolysis, and stent placement. However, the effectiveness and timing of anticoagulation and interventional therapies remain unclear.
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门静脉血栓形成的流行病学、诊断和治疗
近年来,肝硬化患者门静脉血栓形成(PVT)的发生率有所增加;血栓形成范围从无症状的部分闭塞到完全闭塞。治疗很困难。对于缺乏静脉曲张出血或肠系膜缺血的急性PVT患者,抗凝治疗可能是最佳的一线治疗。微创治疗方案包括机械取栓、化学溶栓和支架置入。然而,抗凝和介入治疗的有效性和时机仍不清楚。
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