Slow Spinal Cord Compression Inducing by Malignant Peripheral Nerve Sheath Tumors in Cotonou

D. Gnonlonfoun, C. Adjien, J. N. Mapaga, L. Hodé, Gérard Goudjinou, A. Sowanou, R. Domingo, Pupchen Gnigone, G. Mambila, D. Affanou, P. K. Ndouongo, D. Houinato
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Abstract

MPNST is a very uncommon malignant type of neoplasm. It is often associated with neurofibromatosis type 1 (von Recklinghausen disease). It involves large anatomical regions, and thus takes on varied clinical presentations. However, bone location of MPNST, particularly in the spinal canal has been poorly described in the literature. We hereby report the case of a 29-year old young man with MPNST in the spinal canal. He presented a slow spinal cord compression confirmed by spinal MRI. MPNST was revealed through histologic and immune histochemical features after tumor resection.
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科托努恶性周围神经鞘肿瘤诱导脊髓缓慢压迫
MPNST是一种非常罕见的恶性肿瘤。它通常与1型神经纤维瘤病(von Recklinghausen病)有关。它涉及大的解剖区域,因此采取不同的临床表现。然而,MPNST的骨位置,特别是在椎管中,在文献中描述得很少。我们在此报告一例29岁的年轻男性在椎管中有MPNST。他表现出缓慢的脊髓压迫,脊髓MRI证实。肿瘤切除后的组织学和免疫组织化学特征显示MPNST。
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