Canagliflozin: SGLT2 inhibitor for treating type 2 diabetes

Future Prescriber Pub Date : 2013-08-01 DOI:10.1002/fps.101
Richard Donnelly PhD, MD, FRCP, FRACP
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Abstract

Canagliflozin is a sodium-glucose transporter protein inhibitor under development for the treatment of type 2 diabetes mellitus; it reduces circulatory glucose by facilitating its urinary excretion. In this Drug profile, Richard Donnelly discusses the need for drugs with a mode of action independent of insulin and considers the efficacy and tolerability of canagliflozin in clinical trials, to date, as well as its potential place in management. Copyright © 2013 John Wiley & Sons, Ltd.

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卡格列净:用于治疗2型糖尿病的SGLT2抑制剂
Canagliflozin是一种正在开发用于治疗2型糖尿病的钠-葡萄糖转运蛋白抑制剂;它通过促进尿液排泄来减少循环中的葡萄糖。在这篇药物简介中,Richard Donnelly讨论了对具有独立于胰岛素的作用模式的药物的需求,并考虑了迄今为止临床试验中canagliflozin的疗效和耐受性,以及它在治疗中的潜在地位。版权所有©2013 John Wiley &儿子,有限公司
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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