Identical STEMI Pattern in Two Siblings with Different Risk Factors

IF 0.8 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Journal Of Cardiovascular Emergencies Pub Date : 2020-09-01 DOI:10.2478/jce-2020-0012
R. Gerculy, Camelia Libenciuc, N. Raț, I. Kovács, M. Chițu, I. Benedek, T. Benedek
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Abstract

Abstract Environmental factors may have an important role in the development of coronary heart disease. However, it is not clearly understood yet how the genetic factors interplay with the environmental ones in the onset of acute myocardial infarction. The early onset of coronary artery disease in cases with a positive family history suggests a certain role of genetic predisposition, but the open question remains: could environmental differences contribute to this predisposition? This case report describes similar coronary angiographic findings of two brothers who developed acute myocardial infarction in their early 40s, after being exposed to different environmental risk factors.
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不同危险因素的两个兄弟姐妹的相同STEMI模式
环境因素可能在冠心病的发生发展中起重要作用。然而,遗传因素与环境因素在急性心肌梗死发病中的相互作用机制尚不清楚。家族史阳性的冠状动脉疾病的早期发病表明遗传易感性的某种作用,但悬而未决的问题仍然存在:环境差异是否有助于这种易感性?本病例报告描述了两兄弟在40岁出头时暴露于不同的环境危险因素后发生急性心肌梗死的相似冠状动脉造影结果。
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0.00%
发文量
4
审稿时长
8 weeks
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