Screening for colorectal cancer in employees of ROSTEСH enterprises in the Sverdlovsk region. Pilot project

Abstract

AIM: to evaluate the pilot program results for colorectal cancer (CRC) screening of the Sverdlovsk region (April — October 2021)PATIENTS AND METHODS: a pilot program of three-stage CRC screening included at the first stage, the fecal immunochemical test was performed (patients aged 45–65 years). The second stage included questionnaire. According to the results of the questioning, patients with a positive fecal test and a potential risk of CRC underwent colonoscopy at the third stage.RESULTS: at the first and second stages, 969 fecal immunochemical tests and questionnaires were performed. In 149 (15.4%) cases, a positive fecal test was detected. In 22 cases, employees with a negative fecal test were referred for colonoscopy according to the results of the questionnaire. At the third stage, 168 screening colonoscopies were performed. In 87 (51.5%) patients, epithelial colorectal neoplasia was detected, adenoma — in 57 (33.7%) cases, adenocarcinoma in 4 (2.4%), including T0 — in 3 patients, T2 — in 1 patient. In 182 cases, neoplasia occurred in 17.6% in the rectum and in 82.4% in the colon.CONCLUSION: colorectal cancer (CRC) screening showed high efficacy.