The Role of Early Vitrectomy in the Healing of Retinal Lesions in Progressive Outer Retinal Necrosis

IF 0.7 Q4 OPHTHALMOLOGY Case Reports in Ophthalmological Medicine Pub Date : 2022-02-27 DOI:10.1155/2022/7636052

H. Riazi-Esfahani, A. Mirzaei, M. Mirghorbani, Fariba Ghassemi, M. Zarei, Elias Khalili Pour, Nazanin Ebrahimiadib

{"title":"The Role of Early Vitrectomy in the Healing of Retinal Lesions in Progressive Outer Retinal Necrosis","authors":"H. Riazi-Esfahani, A. Mirzaei, M. Mirghorbani, Fariba Ghassemi, M. Zarei, Elias Khalili Pour, Nazanin Ebrahimiadib","doi":"10.1155/2022/7636052","DOIUrl":null,"url":null,"abstract":"Purpose To report on the efficacy of early pars plana vitrectomy (PPV), silicone oil (SO) tamponade, and intravitreal ganciclovir injection in the treatment of a case with progressive outer retinal necrosis (PORN). Case Presentation. A 33-year-old man with a history of shingles on the chest skin 2.5 months ago presented with progressive vision loss in both eyes over the past 20 days. Fundus examination revealed retinal necrosis with perivascular clearance. Human immunodeficiency virus (HIV) infection was confirmed by western blot analysis. Treatment with intravenous acyclovir and intravitreal ganciclovir injections was unable to stop the progression of retinitis. Along with highly active antiretroviral therapy, the patient underwent PPV with SO tamponade and intravitreal ganciclovir injection in both eyes. A few days after surgery, retinal lesions started to improve. Conclusion Early PPV, SO tamponade, and intravitreal ganciclovir injection may be considered an effective intervention in PORN patients with an unfavorable response to medical treatment.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2022-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Ophthalmological Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2022/7636052","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose To report on the efficacy of early pars plana vitrectomy (PPV), silicone oil (SO) tamponade, and intravitreal ganciclovir injection in the treatment of a case with progressive outer retinal necrosis (PORN). Case Presentation. A 33-year-old man with a history of shingles on the chest skin 2.5 months ago presented with progressive vision loss in both eyes over the past 20 days. Fundus examination revealed retinal necrosis with perivascular clearance. Human immunodeficiency virus (HIV) infection was confirmed by western blot analysis. Treatment with intravenous acyclovir and intravitreal ganciclovir injections was unable to stop the progression of retinitis. Along with highly active antiretroviral therapy, the patient underwent PPV with SO tamponade and intravitreal ganciclovir injection in both eyes. A few days after surgery, retinal lesions started to improve. Conclusion Early PPV, SO tamponade, and intravitreal ganciclovir injection may be considered an effective intervention in PORN patients with an unfavorable response to medical treatment.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

早期玻璃体切除术在进行性视网膜外坏死视网膜病变愈合中的作用

目的报道早期玻璃体平面膜切除(PPV)、硅油(SO)填塞、玻璃体内注射更昔洛韦治疗1例进行性视网膜外坏死(PORN)的疗效。案例演示。33岁男性，2.5个月前胸部皮肤有带状疱疹病史，在过去20天内双眼视力逐渐丧失。眼底检查显示视网膜坏死伴血管周围清除。免疫印迹分析证实为人类免疫缺陷病毒(HIV)感染。静脉注射阿昔洛韦和玻璃体内注射更昔洛韦无法阻止视网膜炎的进展。在高活性抗逆转录病毒治疗的同时，患者接受了双眼SO填塞和玻璃体内注射更昔洛韦的PPV。手术后几天，视网膜病变开始好转。结论早期PPV、SO填塞和玻璃体内注射更昔洛韦可作为治疗不良PORN患者的有效干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Case Reports in Ophthalmological Medicine OPHTHALMOLOGY-

自引率

0.00%

发文量

审稿时长

14 weeks