Eimeria control in baby alpacas using toltrazuril as a prophylactic measure in humid Puna

Diana Sánchez-Herencia, Guiulfo Mamani-Mango, P. Coila-Añasco
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Abstract

An effective concentration of toltrazuril to prophylactics in the control of eimerias and determine the prophylactic dose against eimerias species was evaluated in cria alpacas of the La Raya research center in Cusco Peru. Fifty cria alpacas of 3-4 months of age. distributed in 5 groups of 10 animals each: G 1 treated with 15 mg/kg of live weight (LW) of toltrazuril orally (VO), G 2 with 18.7 mg/kg BW/PO, G 3 with 22.5 mg/kg, G 4 with 30 mg/kg and G 5 without any dosage (control group). All dosage was given orally. Fecal analysis was performed using the modified McMaster technique at time 0 ad seven days later. Data were analyzed using analysis of variance and a Fisher test was done to determine statistical significance. The results indicate that using toltrazuril 15 mg/kg BW and 18.7 mg/kg BW, only small species such as Eimeria punoensis E. alpacae and E. lamae are controlled, but not the large species ( E. macusaniensis ) and with 22.5 and 30 mg/kg LW, in addition to controlling small species, the elimination of E. macusaniensis oocysts is also significantly reduced (p≤0.05). It is concluded that the prophylactic doses to control eimerias in baby alpacas is 22.5 and 30 mg/kg BW, with a single oral application, which manages to control the four species registered in this work.
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托曲祖利防治湿润普纳地区羊驼幼羊艾美耳虫的研究
在秘鲁库斯科La Raya研究中心的cria羊驼中评价了妥曲祖利预防艾美拉蝇的有效浓度和预防艾美拉蝇的剂量。50头3-4个月大的cria羊驼。随机分为5组,每组10只,g1组口服托曲祖利15 mg/kg活重,g2组口服18.7 mg/kg BW/PO, g3组口服22.5 mg/kg, g4组口服30 mg/kg, g5组不给药(对照组)。所有剂量均为口服。在第0和7天后使用改良的麦克马斯特技术进行粪便分析。数据分析采用方差分析和Fisher检验来确定统计显著性。结果表明,施用15 mg/kg BW和18.7 mg/kg BW时,仅能控制羊艾美耳虫和跛足艾美耳虫等小种,而施用22.5和30 mg/kg LW时,对大种(马桑艾美耳虫)无抑制作用,除控制小种外,马桑艾美耳虫卵囊的消除率也显著降低(p≤0.05)。结果表明,预防剂量分别为22.5 mg/kg BW和30 mg/kg BW,口服一次,可有效控制本研究记录的4种羊驼艾美耳虫。
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