Mathematical modelling of COVID-19 pandemic in Pakistan with optimal control

Shakira Hussain, Naveed Sheikh, M. Anjum, A. Raza, Rabail Rizvi
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引用次数: 1

Abstract

We propose an innovative mathematical modeling to examine the previous coronavirus disease of 2019 pandemic or (COVID-19). This analysis has been performed qualitatively through differential equation stability theory, as well as the basic reproductive value, which indicates a pandemic index, then calculated from the maximum eigenvalue of the subsequent matrix. We establish the global asymptotic stability criteria for such disease-free state. The actual COVID-19 occurrence documents and data from 01 July, 2021 to 14 August, 2022 in Pakistan are analyzed for estimation methods, leading in fitted values for biological parameters. Sensitivity analyzation is used to identify the much more relevant attributes in the developed framework. This scientific research revealed a deterministic computational formula that assesses the impact of various mitigation measures on the propagation of COVID-19 in a worldwide population. The analysis will concentrate on Pakistan, and relevant data gathered out of that region. If the method were modified for the total number of COVID-19 reported patients as well as the total number of active patients in the Pakistan region, infection rates would be approximated fairly. This research will in some way give government authorities including local hospitals additional knowledge about how to enhance precautionary efforts to minimize infection propagation.
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基于最优控制的巴基斯坦COVID-19大流行数学模型
我们提出了一个创新的数学模型来检验2019年大流行或(COVID-19)之前的冠状病毒疾病。这一分析是通过微分方程稳定性理论以及表示流行病指数的基本繁殖值进行定性分析的,然后从随后的矩阵的最大特征值计算。我们建立了这种无病状态的全局渐近稳定性判据。对巴基斯坦2021年7月1日至2022年8月14日的实际COVID-19发病文件和数据进行了分析,以确定估算方法,从而得出生物学参数的拟合值。敏感性分析用于识别开发框架中更相关的属性。这项科学研究揭示了一个确定性计算公式,可以评估各种缓解措施对COVID-19在全球人口中传播的影响。分析将集中在巴基斯坦,以及从该地区收集的相关数据。如果根据巴基斯坦地区报告的COVID-19患者总数和活跃患者总数对该方法进行修改,则感染率将得到相当近似的结果。这项研究将以某种方式为包括地方医院在内的政府当局提供有关如何加强预防工作以尽量减少感染传播的额外知识。
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