Comparison of Outcome Between Single Stage Dorsolateral Onlay Buccal Mucosal Graft Urethroplasty and Johanson’s Staged Urethroplasty for Treatment of Long Segment Anterior Urethral Stricture

Shiba Prasad Nandy, Ujjal Barua, M. Alamgir, S. Khan, Md Rafiqul Islam, Md Monowar Ul Hoque
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Abstract

Background: Urethroplasty is the treatment of choice for long segment anterior urethral stricture. Various types of graft can be used as substitution, but now a day Buccal Mucosal Graft (BMG) is more popular with very promising results. This study was conducted to compare the outcome between dorsolateral free BMG graft and traditional staged reconstruction technique.   Materials and methods: This was a hospital based quasi experimental study done prospectively on 64 patients, dividing in two groups, dorsolateral onlay BMG Urethroplasty (Group A) and Johanson’s staged Urethroplasty (Group B) from January 2016 to June 2018 for long segment (3080mm) anterior urethral stricture with a minimum 06 months follow-up. Two patients were failed to attened at follow up clinic were excluded from the study. Data were analyzed by student’s t test, and chi-square test where appropriate.   Results: Total 62 patients were included in results (2 lost in follow-up) 32 patients with BMG (Group A) and 30 patients with Johanson’s urethroplasy (Group B) in 6 months follow-up where success rate of group A was 90.7% and group B 63.3% which is statistically significant. At the end of six months 22 patients (68.8%) in Group A had peak urnary flow rate more than 15 ml/sec, whereas only nine patients (33.3%) had had such flow rate in B group. Post operative complications were significantly higher in Group B. Eight patients (26.7%) in Group B had developed fistula and eleven patients (36.7%) had recurrence in Group B which is significantly higher then Group A.   Conclusions: Dorsolateral onlay BMG urethroplasty is comparatively an effective technique with excellent functional outcome for long segment an- terior urethral stricture and feasible with good short term success. JCMCTA 2020 ; 31 (1) : 31-37
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单期背外侧颊黏膜移植尿道成形术与johnson分期尿道成形术治疗长段前尿道狭窄的疗效比较
背景:尿道成形术是治疗长段前尿道狭窄的首选方法。各种类型的移植物都可以作为替代,但目前口腔粘膜移植物(BMG)更受欢迎,效果很好。本研究比较背外侧游离BMG移植与传统分期重建技术的效果。材料与方法:本研究是一项基于医院的准实验研究,于2016年1月至2018年6月对64例长段(3080mm)前尿道狭窄患者进行前瞻性研究,分为两组,a组和Johanson分期尿道成形术(B组)。2例未到随访诊所就诊的患者被排除在研究之外。数据分析采用学生t检验,适当时采用卡方检验。结果:结果共纳入62例患者(随访丢失2例),BMG患者32例(A组),约翰逊氏尿道成形术患者30例(B组),随访6个月,A组成功率90.7%,B组成功率63.3%,差异有统计学意义。6个月后,A组22例(68.8%)患者尿流量峰值大于15ml /sec,而B组仅有9例(33.3%)患者尿流量峰值大于15ml /sec。B组术后并发症发生率明显高于a组,B组8例(26.7%)出现瘘道,B组11例(36.7%)出现复发,明显高于a组。结论:背外侧膀胱尿道成形术是治疗长段前尿道狭窄的一种较为有效的技术,功能预后良好,短期成功可行。Jcmcta 2020;31 (1): 31-37
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