Uji UJI EFEKTIVITAS GEL EKSTRAK ETANOL 70% GETAH GAMBIR (Uncaria gambir. Roxb) dan BETADINE TERHADAP LUKA SAYAT PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI:10.36656/jpfh.v5i1.1078

S. Sulasmi

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Abstract

Gambir (Uncaria gambir. Roxb) contains flavonoids, tannins, saponins and alkaloids that can help heal wounds. One of the main ingredients that gambir contains is catechins . Catechins are flavonoid compounds with anti-inflammatory, antioxidant and antibacterial properties derived from Gambir. This study aimed to compare wound healing time between ethanolic extracts of 70% gambir resin gel (Uncaria gambir. Roxb) with betadin preparations in male Sprague dawley rats (Rattus norvegicus). A total of 9 white rats (Rattus norvegicus) strain Sprague dawley were divided into 3 groups, a negative control group for gel base treatment and a positive control group for gambir sap gel preparations (Uncaria gambir. Roxb) betadine comparison group. This study was conducted by experimental method with a post-trial controlled group design. Each group is colored with group preparations, the treatment is carried out 3 × 1 every day. Wound healing time was analyzed by a one-way Anova test on spss. Healing ingroup I was 10.6 days, in group II, 10.3 days in group III and 9.3 days.

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测试乙醇提取物凝胶70%碱液(Uncaria GAMBIR)的有效性。Roxb)和BETADINE用于雄性白老鼠(Rattus norvegicus)的出口伤口

甘比尔(Uncaria Gambir)。Roxb)含有类黄酮、单宁、皂苷和生物碱，可以帮助伤口愈合。冈比亚茶的主要成分之一是儿茶素。儿茶素是一种黄酮类化合物，具有抗炎、抗氧化和抗菌的特性。本研究旨在比较70%甘比亚树脂凝胶(Uncaria gambir)乙醇提取物在伤口愈合时间上的差异。β素制剂对雄性褐家鼠(Rattus norvegicus)的影响。将9只褐家鼠(Rattus norvegicus) Sprague dawley家鼠分为3组，凝胶基治疗为阴性对照组，甘比尔树液凝胶制剂为阳性对照组。Roxb)他定对照组。本研究采用实验方法，采用试验后对照组设计。每组用分组制剂着色，每天进行3 × 1次治疗。伤口愈合时间采用spss单因素方差分析。ⅰ组愈合时间为10.6 d，ⅱ组愈合时间为10.3 d，ⅲ组愈合时间为9.3 d。

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Jurnal Penelitian Farmasi & Herbal

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