Predictors of three-year survival in hospitalized patients with atrial flutter

Abstract

The aim – to estimate the survival analysis of patients with atrial flutter after index hospitalization during a three-year follow-up and to determine independent predictors of survival.Materials and methods. The one-center prospective study included 126 patients with various forms of AFL, among them 86 (68.3 %) men and 40 (31.7 %) women, the median age was 65.5 (quartiles 55–73) years. The median follow-up was 26 (quartiles 1–46) months after index hospitalization. Survival analysis was performed by Cox regression for continuous variables, also by estimating Kaplan – Meier curves and by χ2 for ranked variables (with more than 2 ranks) and using Cox’s F-test for binary variables.Results. During the three-year follow-up period 22 (17.5 %) patients died. The 36-months cumulative survival rate was 80.9 %. In multivariate Cox regression analysis presence of decreased left ventricular ejection fraction, left ventricular wall hypertrophy, previous episodes of AFL, hemodynamic instability during AFL and chronic kidney disease (p<0.05) were significant risk factors associated with mortality.Conclusion. The cumulative survival rate at 36 months of follow-up was 80.9 %. Independent predictors of poor survival are decreased left ventricular ejection fraction, left ventricular wall hypertrophy, presence of previous episodes of AFL, hemodynamic instability during AFL, chronic kidney disease.