Review on Diabetic Foot Ulcers and Its Herbal Approach to Treatment

Q4 Pharmacology, Toxicology and Pharmaceutics Hacettepe University Journal of the Faculty of Pharmacy Pub Date : 2023-05-20 DOI:10.52794/hujpharm.1167357
Het Talati̇, P. Bhatt
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Abstract

Diabetes, a silent killer and globally renowned disease, has enormously afflicted most parts of the world causing serious health issues to an individual, many of which suffer financially. There are several outbreaks of this disease, but diabetic foot ulcer is a dreadful situation imparting harsh skin ailments to an individual’s feet. The etiology of these ulcers includes high glucose levels, improper foot hygiene, etc. The pathophysiology of diabetic foot ulcers involves oxidative stress to the nerve tissues and other complications leading to loss of sensation in the patient’s feet along with skin dryness. Many times, diabetes remains undiagnosed but the foot ulcers can be evaluated by the latest electro-diagnostic, radiological, or vascular studies. Once identified, they can be treated with several topical antibiotics and certain foot assistance methods. Besides allopathic medication, one can also opt for herbal treatment as many herbal species are still unnoticed having specific phytochemicals and ought to be an ultimate source for wound healing, some of them are Radix rehmanniae, Martynia annua, Cortex phellodendri, Angelica dahurica, and Moringa oleifera A few of these plant species possess anti-oxidant, anti-bacterial, and other potent therapeutic properties which enhance the wound healing process as per its physiology and with minimal side effects. Some Ayurvedic formulations like Jatyadi Ghrita also contribute efficiently to this ailment that can be applied to foot ulcers to gain positive results.
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糖尿病足溃疡及其中药治疗综述
糖尿病是一种无声的杀手和全球知名的疾病,严重影响着世界大部分地区,给个人造成严重的健康问题,其中许多人遭受经济损失。这种疾病有几次爆发,但糖尿病足溃疡是一种可怕的情况,会给个人的脚带来严重的皮肤疾病。这些溃疡的病因包括高血糖、不适当的足部卫生等。糖尿病足溃疡的病理生理包括神经组织的氧化应激和其他并发症,导致患者足部感觉丧失和皮肤干燥。很多时候,糖尿病仍然无法确诊,但足部溃疡可以通过最新的电诊断、放射学或血管研究来评估。一旦确定,可以用几种局部抗生素和某些足部辅助方法进行治疗。除了对抗疗法药物外,人们还可以选择草药治疗,因为许多草药物种仍未被注意到,它们含有特定的植物化学物质,应该是伤口愈合的最终来源,其中一些是地黄、黄藤、黄柏、白芷和辣木。和其他有效的治疗特性,促进伤口愈合过程根据其生理和最小的副作用。一些阿育吠陀配方,如Jatyadi Ghrita,也有助于有效地治疗这种疾病,可以应用于足部溃疡,以获得积极的效果。
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来源期刊
Hacettepe University Journal of the Faculty of Pharmacy
Hacettepe University Journal of the Faculty of Pharmacy Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
0.60
自引率
0.00%
发文量
18
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