Studies on Synthesis of Aldimines: Part-III. Synthesis, Spectral Characterization and Bioactivity of Salicylaldimines

C. J. Patil, M. Patil, M. C. Patil
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Abstract

Compounds containing >C=N(azomethine) were prepared from Salicylaldehyde with Aniline derivatives by conventional chemical synthesis method. The products are tested in process and the completion of reaction product formation was ascertained by TLC. The final products were characterized by physical viz. m.p., analytical viz. TLC, Instrumental viz. UV-Vis and FTIR spectral techniques. Results showed that all the marked activity coefficients(biopotential) for the studied compounds are less than the standard drug, Ketoconazole.
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醛二胺的合成研究——第三部分。水杨醛二胺的合成、光谱表征及生物活性研究
以水杨醛和苯胺衍生物为原料,采用常规化学合成方法制备了含>C=N(亚甲基)的化合物。用薄层色谱法测定了反应产物的生成是否完成。最终产物采用物理质谱仪、薄层色谱法、紫外可见光谱法和红外光谱法进行表征。结果表明,所研究化合物的活性系数(生物电势)均小于标准药物酮康唑。
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