Uric Acid as a Risk Factor for Cardiovascular Diseases

IF 0.3 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Rational Pharmacotherapy in Cardiology Pub Date : 2022-09-08 DOI:10.20996/1819-6446-2022-08-15
A. Safaryan, A. Lishuta, D. Nebieridze
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Abstract

Recently, hyperuricemia and its association with cardiovascular disease have been receiving more and more attention. The article talks about the role of uric acid in the body, the reasons for its increase and the impact of elevated uric acid levels on the cardiovascular system. The mechanisms of influence of hyperuricemia on the development and progression of cardiovascular diseases are presented. Medicinal and non-drug ways to reduce the level of uric acid in the blood are considered. From non-drug methods, attention is focused on the hypopurine diet, adequate drinking regimen and normalization of body weight. Separately, the effect on the level of uric acid of various drugs used in clinical practice is considered. In the light of current clinical guidelines, the issue of the need to prescribe drug therapy for asymptomatic hyperuricemia is discussed.
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尿酸是心血管疾病的危险因素
近年来,高尿酸血症及其与心血管疾病的关系越来越受到人们的关注。本文讨论了尿酸在体内的作用,其增加的原因以及尿酸水平升高对心血管系统的影响。现就高尿酸血症对心血管疾病发生发展的影响机制作一综述。药物和非药物的方式来降低尿酸在血液中的水平被考虑。从非药物方法来看,关注的重点是低嘌呤饮食,适当的饮酒方案和体重的正常化。另外,还考虑了临床使用的各种药物对尿酸水平的影响。根据目前的临床指南,讨论了无症状高尿酸血症需要药物治疗的问题。
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来源期刊
Rational Pharmacotherapy in Cardiology
Rational Pharmacotherapy in Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
1.00
自引率
50.00%
发文量
79
审稿时长
6 weeks
期刊介绍: The primary goals of the Journal are consolidation of information on scientific and practical achievements in pharmacotherapy and prevention of cardiovascular diseases and continuing education of cardiologists and internists. The scientific concept of the edition suggests the publication of information on current achievements in cardiology, the results of national and international clinical trials. The Journal publishes original articles on the results of clinical trials designed to study the effectiveness and safety of drugs, analysis of clinical practice and its compliance with national and international recommendations, expert s’ opinions on a wide range of cardiology issues, associated conditions and clinical pharmacology. There is a heading “Preventive cardiology and public health” in the Journal to stimulate research interest in this highly demanded area. Memories of the outstanding people in medicine including cardiology, which are of great interest to historians of medicine, are published in "Our Mentors” heading.
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