Bio Technological Intervention with Platelet Rich Plasma for Assisted Regeneration of Sole

S. Shrivastava, S. Naik, Bhushan Patil, Pankaj Kharabe, Anurag Gupta, Swapnil Joshi
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Abstract

With the advent of Regenerative medicine products in medicine, newer solutions are getting evolved for complex conditions. The Cellular therapies offer a new ray of hope by inducing regeneration of tissue at the site of damage. The cellular therapy led by platelet rich plasma (PRP) is one such key regenerative product. But there is a huge variability in its usage, particularly for wounds. The standardisation for clinical usage is not yet evolved, hence limiting the clinical application of the same. The authors have developed a standard protocol “STARS” therapy, which utilises PRP as biotechnological tool, re-engineering the damaged tissue and gradually assisting the regeneration. In this study we report 8 cases of wounds / ulcers over the sole being treated by it. The results are excellent and offer a milestone solution to non-healing wounds/ ulcers over soles. These wounds are otherwise, very difficult to treat particularly as they are associated with high risks factors such as infection, Diabetes and old age. They are under constant pressure due to weight bearing and give way easily and do not heal. The bioenginreeing of the sole tissues through PRP led STARS intervention is safe, effective and easily reproducible.
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富血小板血浆生物技术干预辅助足底再生
随着再生医学产品在医学领域的出现,新的解决方案正在为复杂的情况而发展。细胞疗法通过诱导损伤部位的组织再生,给人们带来了新的希望。以富血小板血浆(PRP)为主导的细胞治疗就是这样一种关键的再生产品。但它的用法有很大的差异,尤其是在伤口上。临床使用的标准化尚未形成,因此限制了其临床应用。作者开发了一种标准方案“STARS”疗法,该疗法利用PRP作为生物技术工具,重新设计受损组织并逐渐帮助再生。在这项研究中,我们报告了8例伤口/溃疡的鞋底被治疗。结果非常好,并提供了一个里程碑式的解决方案,无法愈合的伤口/溃疡的鞋底。否则,这些伤口很难治疗,特别是因为它们与感染、糖尿病和老年等高风险因素有关。它们承受着持续的压力,因为要承受重量,很容易脱落,而且不愈合。通过PRP引导STARS介入对足底组织进行生物工程,安全、有效、易复制。
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