"Antioxidant Capacity and Antitumoral Activity of Citrus Paradisi Essential Oil"

Biomedical Journal of Scientific & Technical Research Pub Date : 2021-12-01 DOI:10.26717/bjstr.2021.40.006434

Ichrak Ben Amor

{"title":"\"Antioxidant Capacity and Antitumoral Activity of Citrus Paradisi Essential Oil\"","authors":"Ichrak Ben Amor","doi":"10.26717/bjstr.2021.40.006434","DOIUrl":null,"url":null,"abstract":"Background: The present study was focused on the study of essential oil extraction from the zest of grapefruit (Citrus paradisi) and the determination of antioxidant and antitumor activities. Methods: Grapefruit essential oil was extracted by hydro distillation, grapefruit essential oil was analyzed for antioxidant potential in the chemical system by the DPPH, ABTS, FRAP test, and scavenging activity of nitric oxide. The cytotoxicity study of grapefruit essential oil was assessed using MTT assay against HeLa and MCF-7 tumor cells. Results: The extraction yield obtained after optimization was 1.32 %. Antioxidant activities were studied using chemical systems. The results have been very interesting since we got 54 %, 83 %, 66 % respectively with DPPH, ABTS, FRAP, and a notable effect to scavenging NO• radical. In addition, a significant antitumor effect of grapefruit essential oil was observed in HeLa and MCF-7 tumor cells. Conclusion: The data serve as the basis for the consumption of Citrus paradisi essential oil, with significant antioxidant activity, with no harmful effect for the normal cells, and with antitumor potential.","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Journal of Scientific & Technical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26717/bjstr.2021.40.006434","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

Abstract

Background: The present study was focused on the study of essential oil extraction from the zest of grapefruit (Citrus paradisi) and the determination of antioxidant and antitumor activities. Methods: Grapefruit essential oil was extracted by hydro distillation, grapefruit essential oil was analyzed for antioxidant potential in the chemical system by the DPPH, ABTS, FRAP test, and scavenging activity of nitric oxide. The cytotoxicity study of grapefruit essential oil was assessed using MTT assay against HeLa and MCF-7 tumor cells. Results: The extraction yield obtained after optimization was 1.32 %. Antioxidant activities were studied using chemical systems. The results have been very interesting since we got 54 %, 83 %, 66 % respectively with DPPH, ABTS, FRAP, and a notable effect to scavenging NO• radical. In addition, a significant antitumor effect of grapefruit essential oil was observed in HeLa and MCF-7 tumor cells. Conclusion: The data serve as the basis for the consumption of Citrus paradisi essential oil, with significant antioxidant activity, with no harmful effect for the normal cells, and with antitumor potential.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

柑桔精油的抗氧化能力和抗肿瘤活性

背景:本研究主要研究了柚子皮精油的提取及抗氧化、抗肿瘤活性的测定。方法:采用水蒸气蒸馏法提取葡萄柚精油，通过DPPH、ABTS、FRAP试验和一氧化氮清除活性分析葡萄柚精油在化学体系中的抗氧化能力。采用MTT法研究葡萄柚精油对HeLa和MCF-7肿瘤细胞的细胞毒性。结果:优化后的提取率为1.32%。用化学体系研究了其抗氧化活性。结果非常有趣，DPPH、ABTS、FRAP分别达到54%、83%、66%，对NO•自由基的清除效果显著。此外，葡萄柚精油对HeLa和MCF-7肿瘤细胞有显著的抗肿瘤作用。结论:该实验结果为枸杞精油具有明显的抗氧化活性，对正常细胞无不良影响，且具有抗肿瘤作用提供了依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Biomedical Journal of Scientific & Technical Research

自引率

0.00%

发文量