Early Complications after Limb Salvage Procedures: Prospective Cross Sectional Study

IF 0.3 Q4 ONCOLOGY International Journal of Surgery-Oncology Pub Date : 2022-01-01 DOI:10.29337/ijsonco.143
Z. Ali, Javeria Saeed, M. Umer
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Abstract

Introduction: Sarcomas are tumors that are mesenchymal in origin involving bone and soft tissues occurring in all age groups. Giant cell tumor, although benign, is locally aggressive and can also destroy the bone. Amputation was once considered primary treatment but now with advancements in diagnostic imaging modalities, surgical procedures and adjuvant therapies, limb salvage surgeries have become the preferred treatment modality. The primary objective of our study was to determine the incidence of early complications occurring within the first thirty days in patients who underwent limb salvage surgery at our hospital. The secondary objective was to assess the association of these complications with patient-related factors, surgical modality, tumor characteristics and neoadjuvant therapy. Methodology: All the patients with bone or soft tissue sarcoma and aggressive giant cell tumors of the extremities who underwent wide excision and limb salvage surgery from February 2020 to December 2021 were included in this study. Data were collected prospectively on follow-up visits in the clinic for one month. Data were compiled and analyzed using SPSS version 22. A p-value of <0.05 was considered significant throughout the study. Results: A total of 60 patients were included in this study. The mean age of the patients was 39.90 years. Bone and soft tissue tumors were found in 35 and 25 patients respectively. A total of 13 patients experienced postoperative is
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残肢保留手术后早期并发症:前瞻性横断面研究
肉瘤是起源于骨和软组织的间充质肿瘤,发生于所有年龄组。巨细胞瘤虽然是良性的,但具有局部侵袭性,也能破坏骨骼。截肢曾经被认为是主要的治疗方法,但现在随着诊断成像方式、外科手术和辅助治疗的进步,保肢手术已成为首选的治疗方式。我们研究的主要目的是确定在我院接受肢体保留手术的患者在前30天内发生的早期并发症的发生率。次要目的是评估这些并发症与患者相关因素、手术方式、肿瘤特征和新辅助治疗的关系。方法:本研究纳入2020年2月至2021年12月行大范围切除保肢手术的四肢骨或软组织肉瘤及侵袭性巨细胞瘤患者。在一个月的临床随访中前瞻性地收集数据。使用SPSS 22对数据进行整理和分析。在整个研究中,p值<0.05被认为是显著的。结果:本研究共纳入60例患者。患者平均年龄39.90岁。骨肿瘤35例,软组织肿瘤25例。术后共13例患者经历
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