Efficacy of partial embolization of splenic artery in patients after hemorrhage of portal genesis

Abstract

Objective. To assess the efficacy of partial embolization of splenic artery in patients after hemorrhage of portal genesis. Materials and methods. Into the investigation 39 patients with verified diagnosis of hepatic cirrhosis, complicated by portal hypertension and hemorrhage from widened varicose esophageal veins, were included. Into the first group (n=17) were included the patients, to whom endoscopic ligature of bleeding varicosities and partial embolization of splenic artery performed; into the second one (n=22) - patients, to whom independent endoscopic ligature of bleeding varicosities performed. The levels of laboratory indices, characterizing hepatic functional state, were assessed monthly. Results. In the first group upon a time a progressive statistically significant improvement of all indices investigated was noted. In the second group a statistically significant improvement of all indices was observed in a period between first and second visit. In further times the changes did not have a statistical significance. While conduction of multifactorial analysis of variance for investigation of embolia impact on the pigmentary metabolism and the system of hemostasis indices a trustworthiness of this impact had grown up upon a time and on the fourth visist became statistically significant. While investigation of the embolization impact on the level of hepatic enzymes and the proteins metabolism indices the trustworthiness of the dependence have been grown upon a time as well, but its gaining of statistical significance was observed on the third visit already. Conclusion. Postoperative period after performance of partial embolization of splenic artery in patients, suffering hemorrhage of portal genesis, is characterized by positive dynamics of laboratory indices in hepatic functional state.