Comparison of Efficacy and Safety of Analog Insulins Vs Human Insulins-Basal Bolus Regimen and Premix Twice Daily Regimen in Indian Hyperglycemia in Pregnancy

Abstract

hypoglycaemia”. Most patients DM a serious situation hyperglycaemia might negatively influence the pregnancy since the duration of implantation and fertilisation. Various complications may affect the child like “macrosomia, Abstract Type 2 diabetes during the course of pregnancy is linked with an unfavourable outcome of maternal foetal. Human insulin is considered as the first choice of drug due to the province of safety use . H owever they are many questions regarding the use of insulin analogues during the time of pregnancy . T he main objective of th is study is to compare the safety and efficacy of human insulin and analogue insulin by understanding the premix daily regimen in hyperglycaemia during pregnancy. All the articles have been classified with an intermediate to high or moderate risk of biasness by showing favourable results for using insulin analogue and human insulin . Therefore, the result ing evidence states that "moderate to high risk of biasness does not allow the conclusion” that the insulin analogue is considered to be more effective while comparing it to the “human insulin for the treatment of pregnant women” suffering from “ Hyperglycemia ”.