Safety and Efficacy of Nalbuphine, Medetomidine, and Azaperone for Immobilizing Aoudad (Ammotragus lervia)

Logan F. Thomas, Chase M. Nunez, Robert O. Dittmar, R. Rech, Jack J. Richison, W. Lance, W. Cook
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引用次数: 1

Abstract

Abstract: We evaluated the safety and efficacy of nalbuphine (40 mg/mL), plus medetomidine (10 mg/mL), plus azaperone (10 mg/mL) under the premixed label NalMed-A. From January to March 2020, 10 aoudad (Ammotragus lervia) were immobilized via dart-gun for seven separate sampling periods for a total of 45 recorded individual immobilization events. Induction and reversal times with NalMed-A were 5.53±2.61 min and (following atipamezole administration) 5.08±2.43 min while previous studies with alpha-2 agonist–ketamine combinations gave median and average induction times of 4.6 min and 11.2 min using medetomidine-ketamine and xylazine-ketamine, respectively. Overall, NalMed-A adequately immobilized aoudad, with 13% incidence of hyperthermia and 2.22% mortality when delivered via dart.
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纳布啡、美托咪定和阿扎哌酮用于固定化大眼的安全性和有效性
摘要:在NalMed-A预混标签下,评价纳布啡(40mg /mL) +美托咪定(10mg /mL) +阿扎哌酮(10mg /mL)的安全性和有效性。从2020年1月至3月,通过飞镖枪对10只大鲵进行了7个不同采样期的固定,共记录了45次个体固定事件。NalMed-A的诱导和逆转时间分别为5.53±2.61 min和5.08±2.43 min(阿替帕唑给药后),而α -2激动剂-氯胺酮联合使用的研究中,美托咪定-氯胺酮和噻嗪-氯胺酮的中位和平均诱导时间分别为4.6 min和11.2 min。总的来说,NalMed-A在体外充分固定,经dart分娩时高热发生率为13%,死亡率为2.22%。
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