Evaluation of Urinary Iodine by Sandell-kolthoff Reaction Method in Urban and Rural Children Referring to the Shiraz Shahid Motahari Clinic and Village of Marvdasht City in 2016 and 2017

Abstract

Background and Objectives: Iodine deficiency affects the population of all age groups, but neonates, infants, pregnant women, and school children constitute the most vulnerable groups. Disorders caused by iodine deficiency are among the major health-nutritional problems in Iran. Because of the importance of this matter, the present study was done to evaluate the status of urinary iodine in 6-16 years old children in urban and rural areas and to compare measurement indices of urinary iodine. Subjects and Methods In this cross-sectional descriptive study, we included 230 6-16 years old children, including 128 urban and 102 rural children. In all samples, the creatinine amount was measured based on the Jaffe reaction, and iodine was measured by the acid digestion method. Since iodine concentration was not normally distributed, the median value of urinary iodine was reported. Also, the urinary iodine/ creatinine (UI/Cr) ratio index was calculated in all samples. Results The median value of urinary iodine in all examined children was 14.30 μg/dL and in children of urban and rural areas were 15.6 and 12.9 μg/dL, respectively. Because these measurements were more than 10 μg/dL, the urinary iodine was sufficient in children of both regions. Based on the median UI/Cr ratio, the iodine excretion was 178.92 μg/g in all children (more than 50 μg/g showing iodine sufficiency). Conclusion Based on median urinary iodine and median UI/Cr ratio, iodine intake in children was normal. Also, according to the present study, there is a fair agreement between both mentioned indices