Late-onset and congenital hearing loss detected using AABR due to congenital cytomegalovirus infection that improved with valganciclovir

IF 1.3 4区 医学 Q3 PEDIATRICS Congenital Anomalies Pub Date : 2022-12-14 DOI:10.1111/cga.12501
Chihiro Morimoto, Toshiya Nishikubo, Tadashi Nishimura, Tomoko Onishi, Masahiro Takeyama, Yumiko Uchida, Shintaro Otsuka, Toshiaki Yamanaka, Tadashi Kitahara
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Abstract

Congenital cytomegalovirus (cCMV) infection is the most common congenital viral infection and is the leading non-genetic cause of sensorineural hearing loss and an important cause of neurodevelopmental disabilities. Auto auditory brainstem response (AABR) is a simple hearing test and used for the purpose of neonatal hearing screening, but can use it for early detection hard of hearing within the study age of the model. We experienced two case of asymptomatic CMV infection in which congenital and late-onset hearing loss were diagnosed early with AABR, and hearing loss improved with valganciclovir.

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使用AABR检测先天性巨细胞病毒感染引起的迟发性先天性听力损失,使用缬更昔洛韦可改善
先天性巨细胞病毒(cCMV)感染是最常见的先天性病毒感染,是感音神经性听力损失的主要非遗传原因,也是神经发育障碍的重要原因。自动听觉脑干反应(AABR)是一种简单的听力测试,用于新生儿听力筛查,但可用于早期检测模型研究年龄内的听力障碍。我们经历了两例无症状CMV感染病例,其中AABR早期诊断为先天性和迟发性听力损失,缬更昔洛韦改善了听力损失。
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来源期刊
Congenital Anomalies
Congenital Anomalies PEDIATRICS-
自引率
0.00%
发文量
49
审稿时长
>12 weeks
期刊介绍: Congenital Anomalies is the official English language journal of the Japanese Teratology Society, and publishes original articles in laboratory as well as clinical research in all areas of abnormal development and related fields, from all over the world. Although contributions by members of the teratology societies affiliated with The International Federation of Teratology Societies are given priority, contributions from non-members are welcomed.
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