Development and evaluation of herbal handwash gel containing Andrographis paniculata alcoholic extract

K. Mishra, Amit Kumar, Aakash Gupta, Sunil Singh, A. Sahu, P. Kashyap, S. Mishra
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引用次数: 1

Abstract

Nowadays, herbs used worldwide due to its medicinal and pharmaceutical potentials. Herbs are also used to prevent human beings from variety of diseases. In the current study, alcoholic extract of which is commonly known as green chiretta used in the development of handwash (herbal). Traditionally, green chiretta was used and known for their different pharmacological action. Alcoholic extract of loaded herbal hand wash prepared by using Carbopol-934 as gelling agent, TEA (triehanolamine) as neutralizer and sodium lauryl sulfoacetate (SLSA) as surfactant. Antibacterial activity of herbal handwash gel evaluated by cup plate method. Sthaphylococcus aureus, Escherihia coli and Bacillus subtilis are used to assess the potential of gel against microorganisms. It shows good potential action against Bacillus subtilis. Physicochemical characterization of herbal handwash gel was performed by morphological study such as odor, color, pH, foam height, consistency and retention as per chemical standards. The developed herbal hand wash formulation showed no side effects and outcomes are in the limits.
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穿心莲醇提物洗手凝胶的研制与评价
如今,由于其药用和制药潜力,草药在世界范围内使用。草药也被用来预防人类的各种疾病。在目前的研究中,其中的酒精提取物俗称青花草用于开发洗手液(中草药)。传统上,人们使用绿切里塔,并以其不同的药理作用而闻名。以carpol -934为胶凝剂,TEA(三乙醇胺)为中和剂,月桂基磺乙酸钠(SLSA)为表面活性剂,制备了载药洗手液的酒精提取物。用杯盘法评价中药洗手液的抗菌活性。金黄色葡萄球菌,大肠杆菌和枯草芽孢杆菌被用来评估凝胶对抗微生物的潜力。对枯草芽孢杆菌具有良好的潜在抑制作用。按照化学标准,通过气味、颜色、pH值、泡沫高度、稠度和保留度等形态学研究对中药洗手凝胶进行理化表征。开发的草药洗手配方显示没有副作用,结果是在极限。
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